Burçak Otlu Sarıtaş

E-mail

burcako@metu.edu.tr

Department

Graduate School of Informatics

From classical approaches to artificial intelligence, old and new tools for PDAC risk stratification and prediction Farinella, Riccardo; Felici, Alessio; Peduzzi, Giulia; Testoni, Sabrina Gloria Giulia; Costello, Eithne; Aretini, Paolo; Blazquez-Encinas, Ricardo; ÖZ, ELİF; Pastore, Aldo; Tacelli, Matteo; Otlu Sarıtaş, Burçak; Campa, Daniele; Gentiluomo, Manuel (2025-07-01) Pancreatic ductal adenocarcinoma (PDAC) is recognized as one of the most lethal malignancies, characterized by late-stage diagnosis and limited therapeutic options. Risk stratification has traditionally been performed usin...
Evaluating topography of mutational signatures with SigProfilerTopography. Otlu Sarıtaş, Burçak; Alexandrov, Ludmil B (2025-05-20)
Rapid Construction Of Mutation-Centric Networks Leveraging Long-Range Interaction Data Otlu Sarıtaş, Burçak; Hüseynov, Ramal (2025-01-15)
Deciphering Sequence Variations And Splicing Sensitivity: Predictive Analysis Of Psi In Srrm4 Response Groups Otlu Sarıtaş, Burçak; Böler, Ümit Sude (2025-01-15)
Comprehensive whole-genome sequencing reveals origins of mutational signatures associated with aging, mismatch repair deficiency and temozolomide chemotherapy Hwang, Taejoo; Sitko, Lukasz Karol; Khoirunnisa, Ratih; Navarro-Aguad, Fernanda; Samuel, David M.; Park, Hajoong; Cheon, Banyoon; Mutsnaini, Luthfiyyah; Lee, Jaewoong; Otlu Sarıtaş, Burçak; Takeda, Shunichi; Lee, Semin; Ivanov, Dmitri; Gartner, Anton (2025-01-13) In a comprehensive study to decipher the multi-layered response to the chemotherapeutic agent temozolomide (TMZ), we analyzed 427 genomes and determined mutational patterns in a collection of ∼40 isogenic DNA repair-defici...
The mutagenic forces shaping the genomes of lung cancer in never smokers Díaz-Gay, Marcos; et. al. (2025-01-01) Lung cancer in never smokers (LCINS) accounts for around 25% of all lung cancers1,2 and has been associated with exposure to second-hand tobacco smoke and air pollution in observational studies3, 4–5. Here we use data from...
Analyzing Replication Timing Of Genes Across Different Cell Lines Otlu Sarıtaş, Burçak; Tercan, Abdullah (2024-12-18)
bindFx: predicting variant effects on transcription factor binding in breast cancer Otlu Sarıtaş, Burçak; Kılınç, Hüseyin Hilmi (2024-09-16)
Topography of mutational signatures in human cancer Otlu Sarıtaş, Burçak (2024-09-16)
Geographic variation of mutagenic exposures in kidney cancer genomes Senkin, Sergey; et. al. (2024-01-01) International differences in the incidence of many cancer types indicate the existence of carcinogen exposures that have not yet been identified by conventional epidemiology make a substantial contribution to cancer burden...

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