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Didem Naz Döken
E-mail
doken@metu.edu.tr
Department
Department of Biology
ORCID
0000-0001-8285-8147
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An alternatively spliced PD-L1 isoform PD-L1∆3, and PD-L2 expression in breast cancers: implications for eligibility scoring and immunotherapy response.
Döken, Didem Naz; Özgül, İbrahim; Yilmazbilek, Irem; Yakicier, Mustafa Cengiz; Karaca, Ezgi; Erson Bensan, Ayşe Elif (2023-09-28)
Targeting PD-1/PD-L1 has shown substantial therapeutic response and unprecedented long-term durable responses in the clinic. However, several challenges persist, encompassing the prediction of treatment effectiveness...
HNRNPA1 Isoform Switch in Breast Cancers
Erson Bensan, Ayşe Elif; Özgül, İbrahim; Erdem, Murat; Döken, Didem Naz (2021-11-01)
Roles of HNRNPA1 are beginning to emerge in cancers; however, mechanisms causing deregulation of HNRNPA1 function remain elusive. Here, we identify and characterize an isoform switch between the 3’-UTR isoforms of HNRNPA1....
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