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GPCR-Gα protein precoupling: Interaction between Ste2p, a yeast GPCR, and Gpa1p, its Gα protein, is formed before ligand binding via the Ste2p C-terminal domain and the Gpa1p N-terminal domain
(Elsevier BV, 2017-12)
G protein coupled receptors bind ligands that initiate intracellular signaling cascades via heterotrimeric G proteins. In this study, involvement of the N-terminal residues of yeast G-alpha (Gpa1p) with the C-terminal ...
Genetic relationship between Kangal, Akbash and other dog populations
(Elsevier BV, 2009-5)
Kangal and Akbash dogs are the two well-known shepherd dog breeds in Turkey. In order to contribute to the understanding of the genetic relationship between Kangal dogs, Akbash dogs and the dogs from different regions of ...
Enhanced expression of HNF4 alpha during intestinal epithelial differentiation is involved in the activation of ER stress
(WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2019-12)
Intestinal epithelial cells are derived from stem cells at the crypts that undergo differentiation into transit-amplifying cells, which in turn form terminally differentiated enterocytes as these cells reach the villus. ...