Plant and food biosecurity: A European Union Network of Excellence

Date

2011-06-01

Author

Gullino, M.
Thomas, J. E.
Henry, C.
Dehne, H.
Suffert, F.
Bonifert, M.
Mumford, J.
Alpas, Hami
Bertin, A.
Marelli, F.
Gamliel, A.
Fletcher, J.
Stack, J.

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Subject Keywords

Plant sciences

URI

https://hdl.handle.net/11511/55483

Journal

PHYTOPATHOLOGY

Collections

Department of Food Engineering, Article

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Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs Verthelyi, D; Ishii, KJ; Gürsel, Mayda; Takeshita, F; Klinman, DM (The American Association of Immunologists, 2001-02-15) Oligodeoxynucleotides (ODN) that contain unmethylated CpG dinucleotides trigger a strong innate immune response in vertebrates. CpG ODN show promise as vaccine adjuvants, anti-allergens, and immunoprotective agents in animal models. Their transition to clinical use requires the identification of motifs that are optimally stimulatory in humans. Analysis of hundreds of novel ODN resulted in the identification and characterization of two structurally distinct "clusters" of immunostimulatory CpG ODN, One cluste...

Citation Formats

M. Gullino et al., “Plant and food biosecurity: A European Union Network of Excellence,” PHYTOPATHOLOGY, pp. 0–0, 2011, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/55483.