Direct Write Patterning of Multiple Proteins and Polymers at the Micrometer and Nanometer Scale

Date

2016-07-17

Author

Bat, Erhan

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https://hdl.handle.net/11511/73959

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Direct Write Protein Patterns for Multiplexed Cytokine Detection from Live Cells Using Electron Beam Lithography Lau, Uland Y.; Saxer, Sina S.; Lee, Juneyoung; Bat, Erhan; Maynard, Heather D. (American Chemical Society (ACS), 2016-01-01) Simultaneous detection of multiple biomarkers, such as extracellular signaling molecules, is a critical aspect in disease profiling and diagnostics. Precise positioning of antibodies on surfaces, especially at the micro- and nanoscale, is important for the improvement of assays, biosensors, and diagnostics on the molecular level, and therefore, the pursuit of device miniaturization for parallel, fast, low-volume assays is a continuing challenge. Here, we describe a multiplexed cytokine immunoassay utilizing...
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Direct measurement of charge transport through helical poly(ethyl propiolate) nanorods wired into gaps in single walled carbon nanotubes Wang, Nan; Yano, Koji; Durkan, Colm; Plank, Natalie; Welland, Mark E.; Zhang, Yan; Ünalan, Hüsnü Emrah; Mann, Mark; Amaratunga, G. A. J.; Milne, William I. (IOP Publishing, 2009-03-11) We report the direct measurement of electrical transport through rod-like polymer molecules, of poly(ethyl propiolate) (PEP), utilizing single walled carbon nanotubes (SWNTs) as electrodes. The electrical properties of the devices were measured (i) before cutting a SWNT, (ii) when a SWNT was cut and (iii) after PEP deposition into the nanoscale gap in a cut SWNT. The gate-dependent electrical properties showed a reduction in current from I-on = 2.4 x 10(-7) A for SWNT devices to I-on = 3.6 x 10(-9) A for PE...
Direct Reconstruction of Pharmacokinetic-Rate Images of Optical Fluorophores From NIR Measurements Alacam, Burak; Yazici, Birsen (Institute of Electrical and Electronics Engineers (IEEE), 2009-09-01) In this paper, we present a new method to form pharmacokinetic-rate images of optical fluorophores directly from near infra-red (NIR) boundary measurements. We first derive a mapping from spatially resolved pharmacokinetic rates to NIR boundary measurements by combining compartmental modeling with a diffusion based NIR photon propagation model. We express this mapping as a state-space equation. Next, we introduce a spatio-temporal prior model for the pharmacokinetic-rate images and combine it with the state...

Citation Formats

E. Bat, “Direct Write Patterning of Multiple Proteins and Polymers at the Micrometer and Nanometer Scale,” 2016, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/73959.