Role of Butyrate in Post-Transcriptional Regulation of Inflammatory Genes by Regulating RNA Binding Proteins

Date

2019-04-27

Author

Torun, Aydan
Enayat, Shabnam
Banerjee, Sreeparna

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https://hdl.handle.net/11511/75665

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Role of butyrate in post-transcriptional regulation of inflammatory genes by regulating RNA binding proteins Torun, Aydan; Banerjee, Sreeparna; Department of Molecular Biology and Genetics (2019) Short chain fatty acids (SCFAs) are generated in the gut by commensal bacteria and are known to reduce inflammation by inhibiting the expression of inflammatory mediators. There are indications that SCFAs can also affect gene expression post transcriptionally. We have hypothesized that butyric acid, a SCFA, can mediate the post-transcriptional regulation of inflammatory mediators such as Cyclooxygenase-2 (COX-2) by affecting the global expression or cytoplasmic translocation of RNA binding proteins (RBPs). ...
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Citation Formats

A. Torun, S. Enayat, and S. Banerjee, “Role of Butyrate in Post-Transcriptional Regulation of Inflammatory Genes by Regulating RNA Binding Proteins,” 2019, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/75665.