Bayesian inference of deterministic MAPK-ERK pathway via reversible jumps Monte Carlo method

Date

2016-06-01

Author

Purutçuoğlu Gazi, Vilda

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https://hdl.handle.net/11511/85490

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Bayesian inference for the MAPK/ERK pathway by considering the dependency of the kinetic parameters Purutçuoğlu Gazi, Vilda (Institute of Mathematical Statistics, 2008-01-01) The MAPK/ERK pathway is one of the major signal transduction systems which regulates the cellular growth control of all eukaryotes like the cell proliferation and the apoptosis. Because of its importance in cellular lifecycle, it has been studied intensively, resulting in a number of qualitative descriptions of this regulatory mechanism. In this study we describe the MAPK/ERK pathway as an explicit set of reactions by combining different sources. Our reaction set takes into account the localization and diff...
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Citation Formats

V. Purutçuoğlu Gazi, “Bayesian inference of deterministic MAPK-ERK pathway via reversible jumps Monte Carlo method,” 2016, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/85490.