A sensitive and selective ratiometric near ir fluorescent probes for zinc and mercury ions based on the distyryl-bodipy fluorophore

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2009

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Atılgan, Serdar

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Near-IR dyes that absorb and emit in the red visible or near-IR region have attracted great interest in the fields of medicinal chemistry and biochemistry for the last few decades. This interest is due to the multiple notes of metal ions in biological and enviromental processes. Therefore the development of cation selective and sensitive sensors have been a hot subject for many researchers. Consequently, fluorescence based sensors are the most efficient and favorable ones among its counterparts in the field of sensor research. In this study, we have targeted to synthesize BODIPY based near-IR dyes as a selective fluorophore for Zn (II) and Hg (II) cations. We have also demonstrated that the versatile BODIPY fluorophore can be functionalized for long wavelength emission on the 3 and 5 position of the BODIPY core with multiple and distinct functional groups in a stepwise manner. Thus we are able to link two BODIPY cores with a different absorption wavelengths to each other first time with click chemistry strategy to generate a chemosensor for Hg (II) cation.

Subject Keywords

Chemistry, Organic

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http://etd.lib.metu.edu.tr/upload/3/12610842/index.pdf
https://hdl.handle.net/11511/18992

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Graduate School of Natural and Applied Sciences, Thesis

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Citation Formats

S. Atılgan, “A sensitive and selective ratiometric near ir fluorescent probes for zinc and mercury ions based on the distyryl-bodipy fluorophore,” Ph.D. - Doctoral Program, Middle East Technical University, 2009.