Synthesis and Rhizopus oryzae mediated enantioselective hydrolysis of α-acetoxy aryl alkyl ketones

Demir, Ayhan Sıtkı
Hamamcı, Haluk
Tanyeli, Cihangir
Akhmedov, Idris M.
Mn(OAc)(3) oxidation of aromatic ketones afforded the alpha-acetoxy ketones in good yield. Selective hydrolysis of the acetoxy ketones by the fungus Rhizopus oryzae yields (R)-hydroxy ketones in high enantiomeric excess.
Tetrahedron Asymmetry


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Citation Formats
A. S. Demir, H. Hamamcı, C. Tanyeli, I. M. Akhmedov, and F. DOGANEL, “Synthesis and Rhizopus oryzae mediated enantioselective hydrolysis of α-acetoxy aryl alkyl ketones,” Tetrahedron Asymmetry, pp. 1673–1677, 1998, Accessed: 00, 2020. [Online]. Available: