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Synthesis and Rhizopus oryzae mediated enantioselective hydrolysis of α-acetoxy aryl alkyl ketones
Date
1998-05-22
Author
Demir, Ayhan Sıtkı
Hamamcı, Haluk
Tanyeli, Cihangir
Akhmedov, Idris M.
DOGANEL, Fatos
Metadata
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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Mn(OAc)(3) oxidation of aromatic ketones afforded the alpha-acetoxy ketones in good yield. Selective hydrolysis of the acetoxy ketones by the fungus Rhizopus oryzae yields (R)-hydroxy ketones in high enantiomeric excess.
Subject Keywords
Manganese(iii) acetate
,
Asymmetric oxidation
,
Carboxylic-acids
,
Bakers-yeast
,
Stereochemistry
,
Hydroxylation
,
Combination
,
Resolution
,
Chemistry
,
Alcohols
URI
https://hdl.handle.net/11511/32186
Journal
Tetrahedron Asymmetry
DOI
https://doi.org/10.1016/s0957-4166(98)00165-7
Collections
Graduate School of Natural and Applied Sciences, Article
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A. S. Demir, H. Hamamcı, C. Tanyeli, I. M. Akhmedov, and F. DOGANEL, “Synthesis and Rhizopus oryzae mediated enantioselective hydrolysis of α-acetoxy aryl alkyl ketones,”
Tetrahedron Asymmetry
, pp. 1673–1677, 1998, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/32186.