Investigation of the Processing of Noun and Verb Words with fMRI in Patients with Schizophrenia

Date

2020-03-01

Author

Nazlı, Şerif Bora
Koçak, Orhan Murat
Kırkıcı, Bilal
Sevindik, Muhammet
Kokurcan, Ahmet

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

138
views

0
downloads

Introduction: Action naming is reported to be more damaged in patients with schizophrenia than object naming. Aim of this study is to understand the cortical mechanism underlying the negative symptoms seen in patients with schizophrenia such as inactivity, restricted behavioral repertoire, by using functional MRI (fMRI) to determine whether the action origin words have a different representation in the brain regions of patients with schizophrenia and healthy individuals. Our hypothesis is that restriction in the repertoire of movement and behavior and the failure of words of "action" than words of "object" are interrelated through the same cortical mechanisms. If this hypothesis is correct, the reason for not taking action in patients with schizophrenia may be improper definition of the action (verb).

Subject Keywords

Language in schizophrenia, Lexical decision task, fMRI

URI

https://hdl.handle.net/11511/43797

Journal

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY

DOI

https://doi.org/10.29399/npa.23521

Collections

Department of Foreign Language Education, Article

Suggestions

OpenMETU
Core

The explanatory relationship among self-esteem, problem solving, ways of coping, social support and suicidal ideation of patients with schizophrenia Alınmış, Raziye Kıvılcım; Fışıloğlu, Hürol; Department of Psychology (2011) This study aimed to explore the relationship among self-esteem, problem solving ability, ways of coping, social support and suicidal ideation of patients with schizophrenia and the differences between these variables according to the existence of suicide attempt of the patients with schizophrenia. In order to analyse the relationship and find out the differences among patients who did and did not attempt suicide, Rosenberg's Self Esteem Scale, Problem Solving Inventory, Turkish Ways of Coping Inventory, Mul...
Parallel changes in serum proteins and diffusion tensor imaging in methamphetamine-associated psychosis Breen, Michael S.; Uhlmann, Anne; Özcan Kabasakal, Süreyya; Chan, Man; Pinto, Dalila; Bahn, Sabine; Stein, Dan J. (2017-03-02) Methamphetamine-associated psychosis (MAP) involves widespread neurocognitive and molecular deficits, however accurate diagnosis remains challenging. Integrating relationships between biological markers, brain imaging and clinical parameters may provide an improved mechanistic understanding of MAP, that could in turn drive the development of better diagnostics and treatment approaches. We applied selected reaction monitoring (SRM)-based proteomics, profiling 43 proteins in serum previously implicated in the...
The Relationship Between Illness Duration And Brain Morphometry in Schizophrenia: Heschl's Gyrus and Prefrontal Cortex Volumetry KARABAY, NURİ; ÖNİZ, ADİLE; Gökçay, Didem; ALPTEKİN, KÖKSAL; Hugdahl, Kenneth; ÖZGÖREN, MURAT (2013-01-01) Introduction: The relationship between brain morphology and illness duration has been observed as a biomarker in psychiatric and neurologic patients, especially in schizophrenia. In this study, we aimed to investigate the relationship between the volumes of two target regions [prefrontal cortex (PFC) and Heschl's gyrus (HG)] and illness duration in schizophrenia. Such measurements can have implications for then understanding of cognitive impairments in schizophrenia.
What is related to the well-being of the siblings of patients with schizophrenia: An evaluation within the Lazarus and Folkman's Transactional Stress and Coping Model Avcioglu, Muazzez Merve; Karancı, Ayşe Nuray; Soygur, Haldun (2019-05-01) Background: Schizophrenia is a chronic mental illness that strongly affects not only the patients with schizophrenia, but also their families and close relatives. So far, family research on patients with schizophrenia has mainly focused on parents, but has neglected siblings. Aim: This study aims to evaluate the well-being of 103 siblings of patients with schizophrenia within the Lazarus and Folkman's Transactional Coping and Stress Model. Materials: A Sociodemographic Information Form, Subjective Well-bein...
Investigation of schizophrenia related genes and pathways through genome wide association studies Döm, Hüseyin Alper; Aydın Son, Yeşim; Department of Bioinformatics (2013) Schizophrenia is a complex mental disorder that is commonly characterized as deterioration of intellectual process and emotional responses and affects 1% of any given population. SNPs are single nucleotide changes that take place in DNA sequences and establish the major percentage of genomic variations. In this study, our goal was to identify SNPs as genomic markers that are related with schizophrenia and investigate the genes and pathways that are identified through the analysis of SNPs. Genome wide associ...

Citation Formats

Ş. B. Nazlı, O. M. Koçak, B. Kırkıcı, M. Sevindik, and A. Kokurcan, “Investigation of the Processing of Noun and Verb Words with fMRI in Patients with Schizophrenia,” NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, pp. 9–14, 2020, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/43797.