A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia

Date

1989-3

Author

Vaddadi, K. S.
Courtney, P. S.
Manku, Mehar S.
Horrobin, David F.
Gilleard, C. J.

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

83
views

0
downloads

This study reports the results of a trial of essential fatty acid (EFA) supplementation in psychiatric patients (predominantly schizophrenics) with movement disorders. Evidence of EFA deficiency in these patients was observed. The antidyskinetic effect of EFA supplementation was marginally significant but not clinically important. However, active treatment produced highly significant improvements in total psychopathology scores and schizophrenia subscale scores, and a significant improvement in memory.

Subject Keywords

Schizophrenia, Tardive dyskinesia, Essential fatty acids, Linoleic acid, Memory

URI

https://hdl.handle.net/11511/51885

Journal

Psychiatry Research

DOI

https://doi.org/10.1016/0165-1781(89)90146-7

Collections

Department of Psychology, Article

Suggestions

OpenMETU
Core

The roles of perceived expressed emotion of the schizophrenic patients and the expressed emotion of their caregivers on symptom severity and quality of life Baştuğ, Gülbahar; Karancı, Ayşe Nuray; Department of Psychology (2008) This study aimed to examine relative effect of perceived expressed emotion of schizophrenic patients and their caregivers’ expressed emotion on the symptom severity and quality of life at the framework of Vulnerability-Stress Model. Before the main study, for evaluating the psychometric properties of the Perceived Expressed Emotion Scale (PEES) a pilot study was conducted with the seventy five patients. Results of the pilot study provided support for the reliability and validity of PEES that had two factors...
In vitro evaluation of zoledronic acid resistance developed in MCF-7 cells Kars, Meltem Demirel; Iseri, Ozlem Darcansoy; Ural, Ali Ugur; Gündüz, Ufuk (2007-11-01) Background: Zoledronic acid is an important osteotropic compound used in combination with anticancer agents to reduce the incidence of hypercalcemia and skeletal morbidity in patients with advanced breast cancer and bone metastases. Ineffectiveness of anticancer drugs during chemotherapy is a frequently observed situation in cancer chemotherapy. The resistance of tumor cells to more than one cytotoxic drugs is defined as multidrug resistance. Drug resistance may be caused by altered gene expression levels a...
A multi-group analysis of the effects of individual differences in mindfulness on nomophobia Arpaci, Ibrahim; Baloğlu, Mustafa; Kesici, Şahin (2019-03-01) This study aimed to investigate the impact of individual differences in mindfulness on nomophobia. We developed and validated two structural models to identify the relationship between mindfulness and nomophobia. The 'Nomophobia Questionnaire' and the 'Mindful Attention Awareness Scale' were used to obtain data from the subjects. One-way MANOVA results suggested a statistically significant difference in nomophobia based on higher versus lower mindfulness. Further, a multi-group analysis was conducted to tes...
Evaluation of Glycomic Profiling as a Diagnostic Biomarker for Epithelial Ovarian Cancer Kim, Kyoungmi; Ruhaak, L. Renee; Uyen Thao Nguyen, Uyen Thao Nguyen; Taylor, Sandra L.; Dimapasoc, Lauren; Williams, Cynthia; Stroble, Carol; Özcan Kabasakal, Süreyya; Miyamoto, Suzanne; Lebrilla, Carlito B.; Leiserowitz, Gary S. (2014-04-01) Background: Prior studies suggested that glycans were differentially expressed in patients with ovarian cancer and controls. Wehypothesized that glycan-based biomarkers might serve as a diagnostic test for ovarian cancer and evaluated the ability of glycans to distinguish ovarian cancer cases from matched controls.
The Impact of Caregivers' Expressed Emotion and the Patients' Perception of Expressed Emotion on the Positive and Negative Symptoms of Patients with Schizophrenia in a Sample From Turkey BAŞTUĞ, GÜLBAHAR; Karanci, Nuray (Kare Publishing, 2015-06-01) The impact of caregivers' expressed emotion and the patients' perception of expressed emotion on the positive and negative symptoms of patients with schizophrenia in a sample from Turkey

Citation Formats

K. S. Vaddadi, P. S. Courtney, M. S. Manku, D. F. Horrobin, and C. J. Gilleard, “A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia,” Psychiatry Research, pp. 313–323, 1989, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/51885.