A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia

Date

1989-3

Author

Vaddadi, K. S.
Courtney, P. S.
Manku, Mehar S.
Horrobin, David F.
Gilleard, C. J.

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This study reports the results of a trial of essential fatty acid (EFA) supplementation in psychiatric patients (predominantly schizophrenics) with movement disorders. Evidence of EFA deficiency in these patients was observed. The antidyskinetic effect of EFA supplementation was marginally significant but not clinically important. However, active treatment produced highly significant improvements in total psychopathology scores and schizophrenia subscale scores, and a significant improvement in memory.

Subject Keywords

Schizophrenia, Tardive dyskinesia, Essential fatty acids, Linoleic acid, Memory

URI

https://hdl.handle.net/11511/51885

Journal

Psychiatry Research

DOI

https://doi.org/10.1016/0165-1781(89)90146-7

Collections

Department of Psychology, Article

Citation Formats

K. S. Vaddadi, P. S. Courtney, M. S. Manku, D. F. Horrobin, and C. J. Gilleard, “A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia,” Psychiatry Research, vol. 27, no. 3, pp. 313–323, 1989, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/51885.