Investigation of four colorectal cancer related single nucleotide polymorphisms in Turkish sporadic colorectal cancer cases

Cumaogullari, O.
Rajabli, F.
İlk Dağ, Özlem
ÖZDAĞ, Hilal


Investigation of the brain connectivity disturbance in dyslexic patients
Rasoulzadeh, Vesal; Ulusoy, İlkay; Kalaycıoğlu, Canan; Department of Biomedical Engineering (2016)
Dyslexia is a learning disability that makes reading a challenge, despite normal level of intelligence and receiving adequate instructions. The core deficit in dyslexia is attributed to phonological processing. It’s been suggested that dyslexia is a disconnection syndrome. In this sense, the major sites of phonological processing in the brain are intact and the interconnection between these areas are disturbed. In this study, the disturbance in dyslectic brains based on effective connectivity models in “pre...
Investigation of seven european colorectal cancer related SNPs in Turkish sporadic colorectal cancer population
Cumaogullari, O.; İlk Dağ, Özlem; Rajabli, F.; Kuzu, A.; ÖZDAĞ, Hilal (2018-07-01)
Investigation of docetaxel and doxorubicin resistance in mcf-7 breast carcinoma cell line
Darcansoy İşeri, Özlem; Gündüz, Ufuk; Department of Biotechnology (2009)
Multidrug resistance phenotype of tumor cells describes resistance to wide range of structurally unrelated anticancer agents and is a serious limitation to effective chemotherapy. It is a multifactor yet not fully elucidated phenomenon by the involvement of diverse cellular pathways. Aim of this study was to investigate the resistance mechanisms developed against docetaxel and doxorubicin that are widely used in the treatment of breast cancer in model cell line MCF-7. Resistant sublines were developed by ap...
Investigation of cellular responses in a patient with STAT1 gain-of-function mutation successfully transplanted with Ruxolitinib bridge therapy and characterization of anti-viral immune responses in DOCK8 deficiency
Kayaoğlu, Başak; Muyan, Mesut; Department of Biology (2023-1)
Gain-of-function mutations (GOF) in the STAT1 gene are associated with impaired STAT1 phosphorylation/dephosphorylation cycle and Th17 deficiency. A sporadic T835M mutation in the STAT1 gene was detected in a patient with chronic mucocutaneous candidiasis (CMC), viral and bacterial infections accompanied by autoimmunity. Here, we aimed to investigate the cellular level defects in the patient and how they were affected by Ruxolitinib treatment and hematopoietic stem cell transplantation (HSCT). We showed tha...
Investigation of multidrug resistance in docetaxel and doxorubicin-resistant MCF-7 cell lines
Iscri, O. Darcansoy; Kars, M. Demirel; Gündüz, Ufuk; Arpaci, F. (2006-06-01)
Citation Formats
O. Cumaogullari, N. TEKİN, F. Rajabli, Ö. İlk Dağ, M. A. KUZU, and H. ÖZDAĞ, “Investigation of four colorectal cancer related single nucleotide polymorphisms in Turkish sporadic colorectal cancer cases,” 2016, vol. 283, Accessed: 00, 2020. [Online]. Available: