Architectures and Functional Coverage of Protein Protein Interface

Date

2009-07-02

Author

Tunçbağ, Nurcan
Nussınov, Ruth
Keskin Özkaya, Zehra Özlem

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https://hdl.handle.net/11511/77595

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Architectures and functional coverage of protein-protein interfaces Tunçbağ, Nurcan; Guney, Emre; NUSSINOV, Ruth; Keskin, Ozlem (2008-09-05) The diverse range of cellular functions is performed by a limited number of protein folds existing in nature. One may similarly expect that cellular functional diversity would be covered by a limited number of protein-protein interface architectures. Here, we present 8205 interface clusters, each representing a unique interface architecture. This data set of protein-protein interfaces is analyzed and compared with older data sets. We observe that the number of both biological and crystal interfaces increase...
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Characterization and prediction of protein interfaces to infer protein-protein interaction networks Keskin, Ozlem; Tunçbağ, Nurcan; GÜRSOY, Attila (2008-04-01) Complex protein-protein interaction networks govern biological processes in cells. Protein interfaces are the sites where proteins physically interact. Identification and characterization of protein interfaces will lead to understanding how proteins interact with each other and how they are involved in protein-protein interaction networks. What makes a given interface bind to different proteins; how similar/different the interactions in proteins are some key questions to be answered. Enormous amount of prot...

Citation Formats

N. Tunçbağ, R. Nussınov, and Z. Ö. Keskin Özkaya, “Architectures and Functional Coverage of Protein Protein Interface,” 2009, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/77595.