Human Corneal Keratocytes Loaded Methacrylated Gelatin Hydrogels as a Model Corneal Stroma

Bektaş, Cemile
Hasırcı, Vasıf Nejat


Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: a synchrotron x-ray scattering study.
Choi, MC; Raviv, U; Miller, HP; Gaylord, MR; Kiriş, Erkan; Ventimiglia, D; Needleman, DJ; Kim, MW; Wilson, L; Feinstein, SC; Safinya, CR (2009-07-22)
Microtubules (MTs), a major component of the eukaryotic cytoskeleton, are 25 nm protein nanotubes with walls comprised of assembled protofilaments built from ab heterodimeric tubulin. In neural cells, different isoforms of the microtubule-associated-protein (MAP) tau regulate tubulin assembly and MT stability. Using synchrotron small angle x-ray scattering (SAXS), we have examined the effects of all six naturally occurring central nervous system tau isoforms on the assembly structure of taxol-stabilized MTs...
Human Gut Commensal Membrane Vesicles Modulate Inflammation by Generating M2-like Macrophages and Myeloid-Derived Suppressor Cells
Bulut, Esin Alpdundar; Kocabas, Banu Bayyurt; Yazar, Volkan; Aykut, Gamze; GÜLER, ÜLKÜ; SALİH, BEKİR; Yilmaz, Naz Surucu; Ayanoğlu, İhsan Cihan; Polat, Muammer Merve; AKÇALI, KAMİL CAN; GÜRSEL, İHSAN; Gürsel, Mayda (2020-11-01)
Immunomodulatory commensal bacteria modify host immunity through delivery of regulatory microbial-derived products to host cells. Extracellular membrane vesicles (MVs) secreted from symbiont commensals represent one such transport mechanism. How MVs exert their anti-inflammatory effects or whether their tolerance-inducing potential can be used for therapeutic purposes remains poorly defined. In this study, we show that MVs isolated from the human lactic acid commensal bacteria Pediococcus pentosaceus suppre...
Human peripheral blood cells differentially recognize and respond to two distinct CpG motifs
Verthelyi, D; Ishii, KJ; Gürsel, Mayda; Takeshita, F; Klinman, DM (The American Association of Immunologists, 2001-02-15)
Oligodeoxynucleotides (ODN) that contain unmethylated CpG dinucleotides trigger a strong innate immune response in vertebrates. CpG ODN show promise as vaccine adjuvants, anti-allergens, and immunoprotective agents in animal models. Their transition to clinical use requires the identification of motifs that are optimally stimulatory in humans. Analysis of hundreds of novel ODN resulted in the identification and characterization of two structurally distinct "clusters" of immunostimulatory CpG ODN, One cluste...
Human tibial bone strength prediction by vibration analysis for diagnosing progressing osteoporosis
Bediz, Bekir; Özgüven, Hasan Nevzat; Department of Mechanical Engineering (2009)
Osteoporosis is a metabolic bone disease that needs to be properly diagnosed. The current diagnosing procedure of osteoporosis is based on the mineral density of bones measured by common methods such as dual energy X-ray absorptiometry (DXA). However, due to the deficiencies and limitations of these common methods, investigations on the utilization of other non-invasive diagnosing methods have been executed. For instance, using vibration measurements seems to be a promising technique in diagnosing metabolic...
Human and Chimpanzee Gene Expression Differences Replicated in Mice Fed Different Diets
Somel, Mehmet; Franz, Henriette; Mueller, Uwe; Lachmann, Michael; Khaitovich, Philipp; Paeaebo, Svante (2008-01-30)
Although the human diet is markedly different from the diets of closely related primate species, the influence of diet on phenotypic and genetic differences between humans and other primates is unknown. In this study, we analyzed gene expression in laboratory mice fed diets typical of humans and of chimpanzees. The effects of human diets were found to be significantly different from that of a chimpanzee diet in the mouse liver, but not in the brain. Importantly, 10% of the genes that differ in their express...
Citation Formats
C. Bektaş and V. N. Hasırcı, “Human Corneal Keratocytes Loaded Methacrylated Gelatin Hydrogels as a Model Corneal Stroma,” 2017, Accessed: 00, 2021. [Online]. Available: