Transkriptomun 3’ Sonu



Modeling the combined effect of RNA-binding proteins and micrornas in post-transcriptional regulation
HafezQorani, Saber; Aydın Son, Yeşim; Kazan, Hilal; Department of Medical Informatics (2015)
Post-transcriptional regulation (PTR) controls the gene expression between transcription and translation. Regulation at this level is carried out by the interactions of trans-acting RNA-binding proteins (RBPs) and microRNAs (miRNAs) with cis-regulatory elements in mRNA. Majority of previous work have focused on the effect of a single factor independent of other co-factors bound to the same mRNA. However, recent studies have shown that RBPs and miRNAs can act in cooperation or competition with each other. In...
Transcriptional engineering of GAP promoter for improved recombinant protein production by Pichia pastoris
Ata, Özge; Çalık, Pınar; Mattanovich, Diethard; Department of Biotechnology (2017)
The objective of this PhD thesis is to enhance the expression strength of glyceraldehyde-3-phosphate dehydrogenase promoter (PGAP) for improved recombinant protein (r-protein) production through modifying the transcription factors (TF) that regulate the functioning of PGAP by transcriptional engineering. PGAP was analyzed in terms of putative TF binding sites. A synthetic library was constructed with distinct regulatory properties through deletion and duplication of these putative transcription factor bindi...
Malware Detection Using Transformers-based Model GPT-2
Şahin, Nazenin; Acartürk, Cengiz; Department of Cybersecurity (2021-11-17)
The variety of malicious content, besides its complexity, has significantly impacted end-users of the Information and Communication Technologies (ICT). To mitigate the effect of malicious content, automated machine learning techniques have been developed to proactively defend the user systems against malware. Transformers, a category of attention-based deep learning techniques, have recently been shown to be effective in solving various malware problems by mainly employing Natural Language Processing (NLP) ...
Transformatıon of The arcades In Beyoğlu
Özkan, Miray; Günay, Baykan; Department of City and Regional Planning (2008)
This thesis is the study of the 19th century arcades in Beyoğlu. The aim is to explore the interrelation between the arcades of Beyoğlu and their surrounding urban structure in both of their formation and transformation processes, and to find out the possible contributions of arcades to the transformation and recentralization process of Đstanbul. The individual stories of the arcades as well as the socio-economic and political conditions are studied to find out the formation and transformation processes. Th...
Transversely izotropik ortamda derinlik migrasyonu uygulanmış CRP gruplarının tomografisi ile hız, derinlik ve anizotropi parametrelerinin belirlenmesi
Kadıoğlu, Selma(2004)
Bu pojede tabaka hızlarının, arayüzey derinliklerinin ve arayüzeylere ait Thomsen's 8 anizotropi parametresinin belirlenmesi için, iki boyutlu düşey simetri eksenli enine (transversely) izotropik ortamda (VTI ortam), yığma öncesi derinlik migrasyonu uygulanmış ortak yansıma noktası gruplarının (CRP gathers) tomografisine dayanan bir yöntem sunulmaktadır. Yöntem, VTI ortam için meteryal parametrelerindeki ve arayüzey derinliklerindeki saçılmalardan dolayı bir CRP ışın çifti boyunca seyahat zamanındaki değişi...
Citation Formats
A. E. Erson Bensan, “Transkriptomun 3’ Sonu,” 2018, Accessed: 00, 2021. [Online]. Available: