Melih Yıldız

E-mail

nisany@metu.edu.tr

Department

Graduate School of Informatics

Under the Shadow: Old-biased Genes Are Subject to Weak Purifying Selection at Both the Tissue- and Cell Type-Specific Levels Yıldız, Melih; İzgi, Hamit; Rahimova, Firuza; Altintaş, Umut Berkay; Şahin, Zeliha Gözde; Somel, Mehmet (2025-10-01) The mutation accumulation hypothesis suggests that weakened purifying selection at old age leads to the accumulation of late-acting deleterious variants in the gene pool, which may contribute to the evolution of ageing. In...

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