Mayda Gürsel

E-mail

mgursel@metu.edu.tr

Department

Department of Biology

ORCID

0000-0003-0044-9054

Scopus Author ID

6701661028

5,6-dimethylxanthenone-4-acetic acid (DMXAA), a partial STING agonist, competes for human STING activation Temizoz, Burcu; Shibahara, Takayuki; Hioki, Kou; Hayashi, Tomoya; Kobiyama, Kouji; Lee, Michelle Sue Jann; Surucu, Naz; Sag, Erdal; Kumanogoh, Atsushi; Yamamoto, Masahiro; Gürsel, Mayda; Ozen, Seza; Kuroda, Etsushi; Coban, Cevayir; Ishii, Ken J. (2024-01-01) 5,6-dimethylxanthenone-4-acetic acid (DMXAA) is a mouse-selective stimulator of interferon gene (STING) agonist exerting STING-dependent anti-tumor activity. Although DMXAA cannot fully activate human STING, DMXAA reached ...
DOCK8 deficiency with hypereosinophilia and the syndrome of inappropriate antidiuretic hormone secretion during herpes infection Yeşil, Ayşe Mete; Kayaoğlu, Başak; Gül, Ersin; Gönç, Nazlı; Özön, Alev; Tezcan, İlhan; Gürsel, Mayda; ÇAĞDAŞ AYVAZ, DENİZ NAZİRE (2023-01-01) Background. Hyperimmunoglobulin E syndrome (HIES) due to dedicator of cytokinesis8 (DOCK8) deficiency may present in infancy and childhood with different clinical features involving recurrent infections, allergic dysregula...
Expanding the Clinical and Immunological Phenotypes and Natural History of MALT1 Deficiency Sefer, Asena Pinar; et. al. (2022-01-01) Purpose MALT1 deficiency is a combined immune deficiency characterized by recurrent infections, eczema, chronic diarrhea, and failure to thrive. Clinical and immunological characterizations of the disease have not been pre...
The silent and dangerous inequity around access to COVID-19 testing: A call to action Comment Batista, Carolina; et. al. (2022-01-01)
Low Density Granulocytes and Dysregulated Neutrophils Driving Autoinflammatory Manifestations in NEMO Deficiency Yilmaz, Naz Surucu; et. al. (2022-01-01) NF-kappa B essential modulator (NEMO, IKK-gamma) deficiency is a rare combined immunodeficiency caused by mutations in the IKBKG gene. Conventionally, patients are afflicted with life threatening recurrent microbial infect...
COVID-19 Vaccine Inequity: High time to calibrate the global moral compass Gürsel, Mayda (2021-12-01)
Achieving global equity for COVID-19 vaccines: Stronger international partnerships and greater advocacy and solidarity are needed Figueroa, J. Peter; et. al. (2021-09-01) Peter Figueroa and co-authors advocate for equity in the worldwide provision of COVID-19 vaccines.
Development and preclinical evaluation of virus-like particle vaccine against COVID-19 infection YILMAZ, İSMAİL CEM; et. al. (2021-09-01) Background Vaccines that incorporate multiple SARS-CoV-2 antigens can further broaden the breadth of virus-specific cellular and humoral immunity. This study describes the development and immunogenicity of SARS-CoV-2 VLP v...
Global public health security and justice for vaccines and therapeutics in the COVID-19 pandemic Hotez, Peter J.; et. al. (2021-09-01) A Lancet Commission for COVID-19 task force is shaping recommendations to achieve vaccine and therapeu-tics access, justice, and equity. This includes ensuring safety and effectiveness harmonized through robust sys-tems of...
Operation Warp Speed: implications for global vaccine security Kim, J. H.; Hotez, P.; Bottazzi, M. E.; Lall, B.; Sheahan, T.; Shoham, S.; Yadav, P.; Batista, C.; Ergonul, O.; Gürsel, Mayda; Figueroa, J. P.; Gilbert, S.; Larson, H.; Wilder-Smith, A.; Hassanain, M.; Kang, G.; Naniche, D.; Strub-Wourgaft, N. (2021-07-01) Several global efforts are underway to develop COVID-19 vaccines, and interim analyses from phase 3 clinical testing have been announced by nine organisations: Pfizer, the Gamaleya Research Institute of Epidemiology and Mi...

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