Detailed Characterization of Structure-Property Relationship of Polyurethanes Synthesized as Biomaterials

2012-12-01
Aksoy, Eda Ayse
Hasırcı, Nesrin
Development of new polyurethanes (PUs) and the modification of the existing ones are still considered as novel areas. This research deals with the preparation of PUs synthesized from its starting materials (without using any solvent, catalyst or chain extender) and examination of the structure property relation through different techniques. Series of segmented elastomeric PU films were synthesized by using different combinations of toluene diisocyanate (TDI) and polyol(polyoxypropylene/polyoxyethylene triol) without using any other ingredients and by one-shot polymerization method. The chemical, thermal and mechanical properties were examined for 2D PU films and the effects of preparation parameters on the structure-property relations were discussed in detail.
JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING

Suggestions

An Information Theoretical Approach for Molecular Communication
Atakan, Baris; Akan, Oezguer B. (2007-12-13)
Molecular communication is a novel communication paradigm which allows nanomachines to communicate using molecules as a carrier. Controlled molecule delivery between two nanomachines is one of the most important challenges which must be addressed to enable the molecular communication. Therefore, it is essential to develop an information theoretical approach to find out molecule delivery capacity of the molecular channel. In this paper, we develop an information theoretical approach for capacity of a molecul...
Preparation and Characterization of Antibacterial Zeolite-Polyurethane Composites
Kamisoglu, K.; Çatman Aksoy, Emine; Akata Kurç, Burcu; Hasırcı, Nesrin; BAÇ, NURCAN (2008-12-05)
In this study, antibacterial properties were induced in polyurethane (PU) films by the incorporation of Ag+-loaded zeolites as fillers. The mechanical and thermal properties of the prepared composites were also investigated. For this purpose, two different types of zeolite microparticles, high-silica zeolite beta crystals and low-silica zeolite A crystals, were synthesized. Ag+ was added by ion exchange, and these particles were incorporated into the PU prepolymer, which was prepared from its main component...
Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells
Ibis, Kubra; Sinoplu, Esra; ÇALIŞKAN, BURCU; Kahraman, Deniz Cansen; Cetin-Atalay, Rengul; BANOĞLU, ERDEN (2021-10-01)
In our effort for the development of novel anticancer therapeutics, a series of isoxazole-piperazine analogues were prepared, and primarily screened for their antiproliferative potential against hepatocellular carcinoma (HCC; Huh7/Mahlavu) and breast (MCF-7) cancer cells. All compounds demonstrated potent to moderate cytotoxicity on all cell lines with IC50 values in the range of 0.09-11.7 mu M. Further biological studies with 6a and 13d in HCC cells have shown that both compounds induced G1 or G2/M arrests...
BIOENGINEERING FUNCTIONAL COPOLYMERS. XV. SYNTHESIS OF ORGANOBORON AMIDE-ESTER BRANCHED DERIVATIVES OF OLIGO(MALEIC ANHYDRIDE) AND THEIR INTERACTION WITH HeLa AND L929 FIBROBLAST CELLS
Kahraman, Gulten; TÜRK, MUSTAFA; Rzayev, Zakir M. O.; Unsal, M. Elif; Soylemez, Ernur (2011-01-01)
Novel bioengineering functional organoboron oligomers were synthesized by (i) amidolysis of oligo(maleic anhydride) (OMA) with 2-aminoethyldiphenylborinate (2-AEPB), (ii) esterification of organoboron oligomer (OMA-B) with alpha-hydroxy-omega-methoxypoly(ethylene oxide) (PEO) as a compatibilizer and (iii) conjugation of organoboron PEO branches (OMA-B-PEO) with folic acid as a taggering agent. Structure and composition of the synthesized oligomers were characterized by FTIR-ART and (1)H ((13)C) NMR spectros...
Investigation of the lipid metabolic changes induced by novel alpha tocopherol analog (TC6OH) in luminal a type breast cancer cells
Gök, Seher; Severcan, Feride; Department of Biology (2017)
Although the traditional chemotherapeutic agents able to suppress breast tumor progression, they are mostly unspecific in their mechanism of action and have toxic effects to normal tissues. Instead, it has been reported that tumor cells are more sensitive to some forms of Vitamin E (VE) and its synthetic derivatives than healthy cells. Studies of drug-cell interactions and understanding the mechanism underlying cytotoxic activity and biological effects at molecular level in cancer model cells are essential ...
Citation Formats
E. A. Aksoy and N. Hasırcı, “Detailed Characterization of Structure-Property Relationship of Polyurethanes Synthesized as Biomaterials,” JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING, pp. 345–354, 2012, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/30283.