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Synthesis and surface modification of polyurethanes with chitosan for antibacterial properties
Date
2014-11-04
Author
Kara, Filiz
AKSOY, EDA AYŞE
YÜKSEKDAĞ, ZEHRANUR
Hasırcı, Nesrin
AKSOY, SERPİL
Metadata
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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Surface modification and providing antibacterial properties to the materials or devices are getting great attention especially in the last decades. In this study, polyurethane (PU) films were prepared by synthesizing them in medical purity from toluene diisocyanate and polypropylene ethylene glycol without using any other ingredients and then the film surfaces were modified by covalent immobilization of chitosan (CH) which has antibacterial activity. CH immobilized PU films (PU-CH) were found to be more hydrophilic than control PU films. Electron Spectroscopy for Chemical Analysis (ESCA) and Atomic Force Microscopy (AFM) analyses showed higher nitrogen contents and rougher surface topography for PU-CH compared to PU films. Modification with CH significantly increased antibacterial activity against Gram positive (Staphylococcus aureus) and Gram negative (Pseudomonas aeruginosa) bacteria. It was observed that the number of bacteria colonies were less about 10(2)-10(5) CFU/mL and number of attached viable bacteria decreased significantly after CH modification of PU films.
Subject Keywords
Polyurethane
,
Chitosan
,
Surface modification
,
Antibacterial
,
Bacterial adhesion
URI
https://hdl.handle.net/11511/31502
Journal
CARBOHYDRATE POLYMERS
DOI
https://doi.org/10.1016/j.carbpol.2014.05.019
Collections
Graduate School of Natural and Applied Sciences, Article
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F. Kara, E. A. AKSOY, Z. YÜKSEKDAĞ, N. Hasırcı, and S. AKSOY, “Synthesis and surface modification of polyurethanes with chitosan for antibacterial properties,”
CARBOHYDRATE POLYMERS
, pp. 39–47, 2014, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/31502.