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Tülin Yanık

Department of Biology
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Neuropeptide Y is involved in the regulation of quiescence of hematopoietic stem cells
Ulum, Baris; Mammadova, Aynura; ÖZYÜNCÜ, ÖZGÜR; Uckan-Cetinkaya, Duygu; Yanık, Tülin; Aerts-Kaya, Fatima (Elsevier BV, 2020-04-01)
Differentiation, self-renewal and quiescence of Hematopoietic stem cells (HSCs) is tightly regulated in order to protect the HSCs from the strain of constant cell division and depletion of the stem cell pool. The neurotran...
The NPY-Y1 receptor for neuropeptide Y is highly expressed on hematopoietic stem cells from bone marrow and cord blood
Ulum, B.; Guney-Esken, G.; ÖZYÜNCÜ, ÖZGÜR; Uckan-Cetinkaya, D.; Yanık, Tülin; Aerts-Kaya, F. (2018-12-01)
A human carboxypeptidase E/NF-alpha 1 gene mutation in an Alzheimer's disease patient leads to dementia and depression in mice
Cheng, Y.; Cawley, N. X.; Yanık, Tülin; Murthy, S. R. K.; Liu, C.; Kasikci, F.; Abebe, D.; Loh, Y. P. (2016-12-06)
Patients with Alzheimer's disease (AD), a common dementia among the aging population, often also suffer from depression. This comorbidity is poorly understood. Although most forms of AD are not genetically inherited, we ha...
Dysregulation of hypothalamic modulation in olanzapine treated male rats
Sezlev-Bilecen, Deniz; AK, MEHMET; Yanık, Tülin (Elsevier BV, 2016-11-03)
The mechanism of weight gain through application of olanzapine, a serotonin and dopamine receptor antagonist has not been fully understood. Weight gain and food intake are under the control of various neurohormones; POMC (...
Effects of risperidone treatment on the expression of hypothalamic neuropeptide in appetite regulation in Wistar rats
Kursungoz, Canan; AK, MEHMET; Yanık, Tülin (2015-01-30)
Although the use of atypical antipsychotic drugs has been successful in the treatment of schizophrenia, they can cause some complications in the long-term use, including weight gain. Patients using these drugs tend to disr...
Weight Gain in Risperidone Therapy Investigation of Peripheral Hypothalamic Neurohormone Levels in Psychotic Patients
Yanık, Tülin; Kursungoz, Canan; Sutcigil, Levent; Ak, Mehmet (Ovid Technologies (Wolters Kluwer Health), 2013-10-01)
The use of antipsychotic drugs has started a new era in the treatment of psychotic disorders. Nevertheless, they cause complications in the long-term treatment, which is mainly weight gain. In this study, we investigated c...
Change of hypothalamic and peripheral levels of appetite related hypothalamic neurohormones in olanzapine treated male Wistar rats
Yanık, Tülin; Sezlev, D.; Ak, M. (2013-07-01)
Investigation of the cellular mechanisms underlying the carboxypeptidase E mutation
Kasikci, F.; Niamh, C. X.; Yanık, Tülin; Loh, P. Y. (2013-07-01)
Atypical anti-psychotics and weight gain: risperidone induced male Wistar rats shows increased food intake and change levels of hypothalamic and circulating appetite related neurohormones
Yanık, Tülin; Kursungoz, C.; Ak, M. (2013-07-01)
The investigation of leptin and hypothalamic neuropeptides role in first attack psychotic male patients: Olanzapine monotherapy
AK, MEHMET; Sezlev, Deniz; Sutcigil, Levent; Akarsu, Suleyman; Ozgen, Fuat; Yanık, Tülin (2013-03-01)
The mechanism underlying the weight gain due to treatment with olanzapine and other second generation antipsychotics has not been fully understood. To examine olanzapine's weight gain effects, we accepted first attack psyc...