Microwave Sensing of Acoustically Induced Local Harmonic Motion: Experimental and Simulation Studies on Breast Tumor Detection

2016-11-01
top, Can Baris
TAFRESHI, Azadeh Kamali
Gençer, Nevzat Güneri
Sensing acoustically induced local harmonic motion using a microwave transceiver system may provide useful information for detecting nonpalpable tumors in dense breast tissue. For this purpose, we propose the harmonic motion microwave Doppler imaging method, in which the first harmonic of the phase modulated signal due to local harmonic motion is sensed. This signal is related to the dielectric, elastic, and acoustic properties of the vibrating region. The purpose of this paper is twofold: 1) to demonstrate the concept of this method with experiments using phantom materials mimicking the elastic and electrical properties of the breast tissue and 2) to investigate the effect of fibroglandular region size and vibration frequency on the received signal, using numerical simulations. A breast phantom with a tumor phantom inclusion (5-mm diameter and 7-mm height) inside fibroglandular region is constructed for the experimental study. The response due to a focused ultrasound probe is linearly scanned at 30-mm depth from the phantom surface, and the Doppler signal level is tracked using a spectrum analyzer. It is shown that the tumor phantom is resolvable inside the surrounding fibroglandular region with about a 3-5-dB decrease in the signal level. The simulations, using the finite-difference time-domain method, show that the received signal level depends on the relative size of the fibroglandular region with respect to the vibrating region size. Further experimental and numerical studies are needed to investigate the feasibility of this method and to optimize the imaging system design.
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES

Suggestions

Received Signal in Harmonic Motion Microwave Doppler Imaging as a Function of Tumor Position in a 3D Scheme
IRGIN, Umit; TOP, Can Baris; TAFRESHI, Azadeh Kamali; Gençer, Nevzat Güneri (2017-02-08)
Harmonic Motion Microwave Doppler Imaging method, which was proposed as an alternative method for breast tumor detection, is a combination of microwave radar and focused ultrasound techniques yielding data depending on electrical and mechanical properties of the tissue. In this study, Harmonic Motion Microwave Doppler Imaging data from a small tumor inside homogeneous fat is analyzed as a function of tumor location on three orthogonal planes using Finite Difference Time Domain simulations. The results show ...
An Improved Receiver for Harmonic Motion Microwave Doppler Imaging
Soydan, Damla Alptekin; Irgin, Umit; Top, Can Baris; Gençer, Nevzat Güneri (2020-03-01)
© 2020 EurAAP.Harmonic motion microwave Doppler imaging is a novel imaging modality that combines focused ultrasound and radar techniques to obtain data based on mechanical and electrical properties of the tissue. In previous experimental studies, the Doppler component of the scattered signal is sensed and used to create 2D images of a tumor inside a homogeneous fat phantom. Due to the drawbacks of the receiver configuration, scanning time was high, the signal-to-noise ratio was low, and the multi-frequency...
Design and realization of a hybrid medical imaging system: harmonic motion microwave doppler imaging
Tafreshi, Azadeh Kamali; Gençer, Nevzat Güneri; Department of Electrical and Electronics Engineering (2016)
Harmonic Motion Microwave Doppler Imaging (HMMDI) is a novel imaging modality to image electrical and mechanical properties of body tissues. This modality is recently proposed by the researchers in the METU EEE department for early-stage diagnosis of cancerous tissues. The main goal of this thesis study is to contribute various stages of the HMMDI's development processes. Speci cally, phantom development, dielectric and elastic characterization of the phantoms, experimental system realization, phantom exper...
Harmonic Motion Microwave Doppler Imaging: A Simulation Study Using a Simple Breast Model
Top, Can Baris; Gençer, Nevzat Güneri (2014-02-01)
A hybrid method for tissue imaging using dielectric and elastic properties is proposed and investigated with simple bi-layered breast model. In this method, local harmonic motion is generated in the tissue using a focused ultrasound probe. A narrow-band microwave signal is transmitted to the tissue. The Doppler component of the scattered signal, which depends on the dielectric and elastic properties of the vibrating region, is sensed. A plane-wave spectrum technique is used together with reciprocity theorem...
2D Simulations Based on General Time-Dependent Reciprocal Relation for LFEIT
KARADAŞ, Mursel; Gençer, Nevzat Güneri (2015-08-29)
Lorentz field electrical impedance tomography (LFEIT) is a newly proposed technique for imaging the conductivity of the tissues by measuring the electromagnetic induction under the ultrasound pressure field. In this paper, the theory and numerical simulations of the LFEIT are reported based on the general time dependent formulation. In LFEIT, a phased array ultrasound probe is used to introduce a current distribution inside a conductive body. The velocity current occurs, due to the movement of the conductiv...
Citation Formats
C. B. top, A. K. TAFRESHI, and N. G. Gençer, “Microwave Sensing of Acoustically Induced Local Harmonic Motion: Experimental and Simulation Studies on Breast Tumor Detection,” IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, pp. 3974–3986, 2016, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/34290.