Free radical scavenging capacity of ethyl acetate extract of Salvia tomentosa

2011-09-01
Onay, Melih
Çoruh, Nursen
Celep, Ferhat
Doğan, Musa
Salvia belongs to the Lamiaceae family and includes nearly90 species in Turkey. Salvia generally is used for treatment ofcolds, bronchitis and epilepsy. It is commonly consumed as a hotdrink. In the current study, ethyl acetate extract ofSalvia tomen-tosawas investigated for its free radical scavenging capacity usingthe 2,2-diphenyl-1-picryl hidrazyl (DPPH) method and its antioxi-dant property was evaluated. Moreover, the extraction procedureapplied toSalvia tomentosayielded a calculated 5.13%. Its scaveng-ing capacity ranged between 0.03 and 1.7 mg/mL and ethyl acetateextract ofS. tomentosahas represented the minimum scavengingactivity of nearly 3% at 0.03 mg/mL and the maximum scaveng-ing activity of 71% at 1.67 mg/mL. The free radical scavengingeffective concentration (EC) ofSalvia tomentosawas found to be0.91±0.005 mg/mL. In conclusion, it can be used as medicinal plantwith antioxidant property for further investigation.