K5 tipi öldürücü maya toksik proteinin yüksek miktarlarda üretilmesi ve saflaştırılması, insan ve bitki patojenik mantarları üzerindeki inhibasyon etkisinin tayini ve endüstriyel amaçlı kullanım için formülasyonunun geliştirilmesi

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2006

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Kepekçi, Remziye Aysun
İzgü, Kadri Fatih
Türeli, Emre Akif

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https://app.trdizin.gov.tr/publication/project/detail/TmpVeE5qWT0
https://hdl.handle.net/11511/49816

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Department of Biology, Project and Design

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Antifungal spectrum determination of the K5 type yeast killer protein on fungi causing spoilage in citrus fruits Kepekçi, Remziye Aysun; İzgü, Kadri Fatih; Department of Biology (2006) Some yeast strains under certain conditions secrete polypeptide toxins which are inhibitory to sensitive fungal cells into the medium. These yeast strains are termed as killer yeasts and their toxins are designated as killer proteins or killer toxins. Killer proteins are classified into 11 typical types (K1-K11). These toxins have different killing mechanisms on sensitive cells. Some of them hydrolyze major cell wall component, beta-1,3- glucans. As mammalian cells lack cell walls research and development o...
K5 Tipi Maya Toksit Proteini İle Yüklenmiş Kitosan Mikro/nanopartiküllerinin Hazırlanması, Karakterizasyonu Ve İnsanda Vajinal Candida Enfeksiyonlarının Topikal Tedavisinden Etkinliklerinin İn-Vitro Olarak Belirlenmesi İzgü, Kadri Fatih(2012-12-31) Kapsam K5 tipi maya toksik proteininin saf halde izolasyonu yapılacak topikal tedavi amaçlı uygulamalar için kitosan nano/mikropartiküllerinde enkapsüle edilecektir. Takiben proteini içeren kitosan partiküllerinin yapısal analizleri, proteini tutma kapasitaleri, proteinin bu partiküller içersindeki stabilitesi ve partiküllerden salım miktarları analiz edilecektir.Sonra vulvovajinal kandidiazise neden olan Candida türlerine karşı etkinlikleri invitro olarak belirlenecektir Yöntem 1. HPLC teknikleri kul...
Antimicrobial spectrum determination of the K5 type yeast killer protein on bacteria causing skin infections and its cell killing activity Gönen, Tuğçe; İzgü, Kadri Fatih; Department of Biology (2006) Some yeast strains secrete extracellular polypeptide toxins known to have potential growth inhibitory activity on sensitive yeast cells. These yeast strains are known as killer yeasts and their toxins are named as killer toxins or killer proteins. Yeast killer proteins are found inhibitory to Gram-positive bacteria in several studies which were based on microbial interactions of the producer strains tested with sensitive strains. K5 type yeast killer protein produced by Pichia anomala NCYC 434 was previousl...
Investigation of cytocidal effect of K5 type yeast killer protein on sensitive microbial cells Sertkaya, Abdullah; İzgü, Kadri Fatih; Department of Biology (2005) Some yeasts secrete polypeptide toxins, which are lethal to other sensitive yeast cells, gram-positive pathogenic bacteria and pathogenic fungi. Therefore these are designated as killer toxins. Killer toxins are suggested as potent antimicrobial agents especially for the protection of fermentation process against contaminating yeasts, biological control of undesirable yeasts in the preservation of foods. Moreover they are promising antimicrobial agents in the medical field; due to immune system suppressing ...
Antimicrobial spectrum determination of the K5 type yeast killer protein and its kinetics of cell killing Türel, Akif Emre; İzgü, Kadri Fatih; Department of Biology (2005) Some yeast strains under certain conditions secrete into the medium polypeptide toxins which are inhibitory to sensitive cells. These yeast strains are termed as killer yeasts and their toxins are designated as killer proteins or killer toxins. Killer proteins are classified into 11 typical types (K1-K11). These toxins have different killing mechanisms on sensitive cells. Some of them hydrolyze major cell wall component β-1,3- glucans. As mammalian cells lack cell walls research and development of novel hig...

Citation Formats

R. A. Kepekçi, K. F. İzgü, and E. A. Türeli, “K5 tipi öldürücü maya toksik proteinin yüksek miktarlarda üretilmesi ve saflaştırılması, insan ve bitki patojenik mantarları üzerindeki inhibasyon etkisinin tayini ve endüstriyel amaçlı kullanım için formülasyonunun geliştirilmesi,” 2006. Accessed: 00, 2020. [Online]. Available: https://app.trdizin.gov.tr/publication/project/detail/TmpVeE5qWT0.