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New insights on commemoration of the dead through mortuary and architectural use of pigments at Neolithic Çatalhöyük, Turkey Schotsmans, E.M.J.; Busacca, G.; Lin, S.C.; Vasić, M.; Lingle, A.M.; Veropoulidou, R.; Mazzucato, C.; Tibbetts, B.; Haddow, S.D.; Somel, Mehmet; Toksoy-Köksal, F.; Knüsel, C.J.; Milella, M. (2022-12-01) The cultural use of pigments in human societies is associated with ritual activities and the creation of social memory. Neolithic Çatalhöyük (Turkey, 7100–5950 cal BC) provides a unique case study for the exploration of li...
Rapid diagnosis of malignant pleural mesothelioma and its discrimination from lung cancer and benign exudative effusions using blood serum Yonar, Dilek; Severcan, Mete; Gurbanov, Rafig; Sandal, Abdulsamet; Yilmaz, Ulku; Emri, Salih; Severcan, Feride (2022-10-01) © 2022Malignant pleural mesothelioma (MPM), an aggressive cancer associated with exposure to fibrous minerals, can only be diagnosed in the advanced stage because its early symptoms are also connected with other respirator...
Effects of a microplastic mixture differ across trophic levels and taxa in a freshwater food web: In situ mesocosm experiment Yıldız, Dilvin; Yalçın, Gülce; Jovanović, Boris; Boukal, David S.; Vebrová, Lucie; Riha, Derya; Stanković, Jelena; Savić-Zdraković, Dimitrija; Metin, Melisa; Akyürek, Yasmin Naz; Balkanlı, Deniz; Filiz, Nur; Milošević, Djuradj; Feuchtmayr, Heidrun; Richardson, Jessica A.; Beklioğlu, Meryem (2022-08-25) © 2022The ubiquitous presence of microplastics (MP) in aquatic ecosystems can affect organisms and communities in multiple ways. While MP research on aquatic organisms has primarily focused on marine ecosystems and laborat...
The ancient DNA and archaeobotanical analysis suggest cultivation of Triticum aestivum subsp. spelta at Yumuktepe and Yenikapi Pottery Neolithic sites in Turkey Degirmenci, Funda O.; ULAŞ, BURHAN; Kansu, Cigdem; Ulug, Asiye; Caneva, Isabella; Asal, Rahmi; Kaya, Zeki (2022-08-01) Archaeobotanical materials subject to aDNA analysis were recovered from Yumuktepe and Yenikapi, two important archaeological sites in Anatolia and date back to the Pottery Neolithic Period i.e., 7th millennium BC. Many cha...
ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2 Huebner, Kerstin; et. al. (2022-08-01) In cancer, the activating transcription factor 2 (ATF2) has pleiotropic functions in cellular responses to growth stimuli, damage, or inflammation. Due to only limited studies, the significance of ATF2 in colorectal cancer...
Structural and functional evaluation mammalian and plant lipoxygenases upon association with nanodics as membrane mimetics. Ulusan, Sinem; Sheraj, Ilir; Stehling, Sabine; Ivanov, Igor; Das, Aditi; Kühn, Hartmut; Banerjee, Sreeparna (2022-07-08)
Capturing Wheat Phenotypes at the Genome Level Hussaın, Babar; et. al. (2022-07-04) Recent technological advances in next-generation sequencing (NGS) technologies have dramatically reduced the cost of DNA sequencing, allowing species with large and complex genomes to be sequenced. Although bread wheat (Tr...
Editorial: Epithelial to Mesenchymal Plasticity in Colorectal Cancer Bocci, Federico; Schneider-Stock, Regine; Banerjee, Sreeparna (2022-06-23)
Freshwater salinisation: a research agenda for a saltier world Cunillera-Montcusí, David; Beklioğlu, Meryem; Cañedo-Argüelles, Miguel; Jeppesen, Erik; Ptacnik, Robert; Amorim, Cihelio A.; Arnott, Shelley E.; Berger, Stella A.; Brucet, Sandra; Dugan, Hilary A.; Gerhard, Miriam; Horváth, Zsófia; Langenheder, Silke; Nejstgaard, Jens C.; Reinikainen, Marko; Striebel, Maren; Urrutia-Cordero, Pablo; Vad, Csaba F.; Zadereev, Egor; Matias, Miguel (2022-05-01) © 2021 The AuthorsThe widespread salinisation of freshwater ecosystems poses a major threat to the biodiversity, functioning, and services that they provide. Human activities promote freshwater salinisation through multipl...
SMN loss dysregulates microtubule-associated proteins in spinal muscular atrophy model Zobaroğlu Özer, Pelin; Koyunoğlu, Dila; Son, Çağdaş Devrim; Erdem-Yurter, Hayat Erdem; BORA, GAMZE (2022-05-01) © 2022 Elsevier Inc.Spinal muscular atrophy (SMA) is a rare neurodegenerative disease caused by the absence of survival motor neuron (SMN) protein. SMN loss results in impairments of the cytoskeleton, including microtubule...
The structural effects of Vitamin A deficiency on biological macromolecules due to ethanol consumption and withdrawal: An FTIR study with chemometrics ELİBOL, BİRSEN; Severcan, Mete; Jakubowska-Dogru, Ewa; DURSUN, İLKNUR; Severcan, Feride (2022-04-01) The structural effects of vitamin A-deficiency were examined on the molecular profiles of biomolecules of male rat hippocampus during prolonged ethanol intake/withdrawal using FT-IR spectroscopy coupled with chemometrics. ...
Disentangling the importance of space and host tree for the beta-diversity of beetles, fungi, and bacteria: Lessons from a large dead-wood experiment Rieker, Daniel; Krah, Franz-S.; Gossner, Martin M.; Uhl, Britta; Ambarlı, Didem; Baber, Kristin; Buscot, François; Hofrichter, Martin; Hoppe, Björn; Kahl, Tiemo; Kellner, Harald; Moll, Julia; Purahong, Witoon; Seibold, Sebastian; Weisser, Wolfgang W.; Bässler, Claus (2022-04-01) © 2022 Elsevier LtdForestry in Europe changed the tree species composition and reduced dead-wood amount and heterogeneity, and therefore negatively affected saproxylic diversity. Efficient conservation requires knowledge a...
TrkA-cholinergic signaling modulates fear encoding and extinction learning in PTSD-like behavior. Yanpallewar, Sudhirkumar; Tomassoni-Ardori, Francesco; Palko, Mary Ellen; Hong, Zhenyi; Kiriş, Erkan; Becker, Jodi; Fulgenzi, Gianluca; Tessarollo, Lino (2022-03-17) Recent studies have suggested that the use of cognitive enhancers as adjuncts to exposure-based therapy in individuals suffering from post-traumatic stress disorder (PTSD) may be beneficial. Brain cholinergic signaling thr...
Genetic diversity and population structure of Salix alba across river systems in Turkey and their importance in conservation management Özdemir Değirmenci, Funda; Çiftçi, Asiye; Acar, Pelin; Kaya, Zeki (2022-03-01) Background Salix alba is a pioneer species of river ecosystems throughout Turkey. Its genetic diversity and population structure across these ecosystems is currently unknown. Aims We investigated genetic diversity in Turki...
Broad maternal geographic origin of domestic sheep in Anatolia and the Zagros Her, Charlotte; Rezaei, Hamid-Reza; Hughes, Sandrine; Naderi, Saeid; Duffraisse, Marilyne; Mashkour, Marjan; Naghash, Hamid-Reza; Balasescu, Adrian; Luikart, Gordon; Jordan, Steve; Ozut, Deniz; KENCE, AYKUT; Bruford, Michael W.; Tresset, Anne; Vigne, Jean-Denis; Taberlet, Pierre; Hanni, Catherine; Pompanon, Francois (2022-03-01) We investigated the controversial origin of domestic sheep (Ovis aries) using large samples of contemporary and ancient domestic individuals and their closest wild relatives: the Asiatic mouflon (Ovis gmelini), the urial (...
Xenogenic Neural Stem Cell-Derived Extracellular Nanovesicles Modulate Human Mesenchymal Stem Cell Fate and Reconstruct Metabolomic Structure DERKUŞ, BURAK; Isik, Melis; Eylem, Cemil Can; ERGİN, İREM; Camci, Can Berk; Bilgin, Sila; ELBÜKEN, ÇAĞLAR; ARSLAN, YAVUZ EMRE; Akkulak, Merve; Adalı, Orhan; KIRAN, FADİME; Okesola, Babatunde O.; NEMUTLU, EMİRHAN; EMREGÜL, EMEL (2022-03-01) Extracellular nanovesicles, particularly exosomes, can deliver their diverse bioactive biomolecular content, including miRNAs, proteins, and lipids, thus providing a context for investigating the capability of exosomes to ...
Present and historical landscape structure shapes current species richness in Central European grasslands Scherreiks, Pascal; Gossner, Martin M.; Ayasse, Manfred; Bluethgen, Nico; Fischer, Markus; Klaus, Valentin H.; Kleinebecker, Till; Neff, Felix; Prati, Daniel; Seibold, Sebastian; Simons, Nadja K.; Weisser, Wolfgang W.; Wells, Konstans; Westphal, Catrin; Thiele, Jan; Ambarlı, Didem (2022-03-01) Context Current diversity and species composition of ecological communities can often not exclusively be explained by present land use and landscape structure. Historical land use may have considerably influenced ecosystem...
Development of ACE2 loaded decoy liposomes and their effect on SARS-CoV-2 for Covid-19 treatment Arısoy, Sema ; Kocas, Meryem; Çomoğlu, Tansel ; Güderer, İsmail; Banerjee, Sreeparna (2022-02-01) SARS-CoV-2 is a novel coronavirus with a positively oriented single-stranded RNA that first appeared in December 2019. In this study, Angiotensin Converting Enzyme 2 (ACE2) loaded decoy liposomes were developed and charact...
Corrosion Resistance and Cytocompatibility of Magnesium-Calcium Alloys Modified with Zinc- or Gallium-Doped Calcium Phosphate Coatings TAMAY, DİLARA GÖKSU; Gokyer, Seyda; Schmidt, Jurgen; Vladescu, Alina; HURİ, PINAR; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin (2022-01-12) In orthopedic surgery, metals are preferred to support or treat damaged bones due to their high mechanical strength. However, the necessity for a second surgery for implant removal after healing creates problems. Therefore...
Establishment of Human Induced Pluripotent Stem Cells from Multiple Sclerosis Patients. Begentaş, Onur Can; Koc, Dilara; Kiris, Erkan (2022-01-06) The patient-derived iPSC lines provide valuable resources as these cells can be utilized to generate human cell types relevant to the disease of interest. In this context, human iPSC-based model systems are particularly us...

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