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Conversion of homochiral amines, beta-amino alcohols and alpha-amino acids to their chiral 2-substituted pyrrole derivatives

Demir, Ayhan Sıtkı
Akhmedov, IM
Sesenoglu, O
Alpturk, O
Apaydin, S
Gercek, Z
Ibrahimzade, N
The conversion of the amino group of chiral amines, amino alcohols, amino acids and their esters into chiral 2-substituted pyrrole derivatives with various halogeno enones is described. The conversion works in good yield and without racemization. The synthesis of 2-phenylpyrrole derivatives was possible with amino alcohols but not with amino acids or their esters