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Controlled-release of a herbicide from cross-linked gelatin microspheres
Date
1993-09-15
Author
AKIN, H
Hasırcı, Nesrin
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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Subject Keywords
Pharmacology
URI
https://hdl.handle.net/11511/54696
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Graduate School of Natural and Applied Sciences, Conference / Seminar
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COMPARATIVE-STUDIES OF SHEEP LUNG AND LIVER NITROFURANTOIN REDUCTASE
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1. Nitrofurantoin reductase which catalyzes the bioactivation of nitrofurantoin was purified to electrophoretic homogenity from sheep liver and lung microsomes, with a yield of 15% and 35%, respectively. The specific activity of both reductases was found to be similar (140 nmol/min/mg protein). 2. The effects of nitrofurantoin and NADPH concentrations, pH, ionic strength, amount of enzyme and reaction period, on the enzyme activity were studied and the optimum conditions for maximum activity of purified fi...
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Biomechanical and histological outcome of combined raloxifene-estrogen therapy on skeletal and reproductive tissues
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Estrogen replacement is a potent therapy for postmenopausal osteoporosis. However, its carcinogenic effects on breasts and the uterus limit its utilization. Raloxifene has estrogen-like effects on bones without the carcinogenic symptoms on breast or uterine tissue. Their individual effects are well characterized, but the results of their interaction remains elusive. In this work, we investigate the consequences of a combined raloxifene/estrogen therapy on bone and uterus with experimental osteoporosis. 40 W...
Differential expressions and functions of phosphodiesterase enzymes in different regions of the rat heart
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Phosphodiesterase enzymes (PDEs) are responsible for the adjustment of cyclic nucleotide levels. Alterations in PDE expressions in different tissues cause conflicts between functional and clinical effects of PDE inhibitors. Therefore, the aim of this study was to investigate the gene and protein expressions and the functional role of PDEs in atrium and ventricle of rat heart The expressions of PDEs were examined in cardiac intact tissues and enzymatically isolated cells. The effects of PDE1-5 inhibitors (vi...
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H. AKIN and N. Hasırcı, “Controlled-release of a herbicide from cross-linked gelatin microspheres ,” 1993, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/54696.