Bone mineral density of ancient Anatolian populations

Ozer, Ismail
Sagir, Mehmet
Baykara, Ismail
Yilmaz, Hakan
Gulec, Erksin
Korkusuz, Feza


Bone generation on PHBV matrices: an in vitro study
Kose, GT; Korkusuz, F; Korkusuz, P; Purali, N; Ozkul, A; Hasırcı, Vasıf Nejat (2003-12-01)
Bone formation was investigated in vitro by culturing rat marrow stromal osteoblasts in biodegradable, macroporous poly(3-hydroxybutyric acid-co-3-bydroxyvaleric acid) (PHBV) matrices over a period of 60 days. Foams were prepared after solvent evaporation and solute leaching. PHBV solutions with different concentrations were prepared in chloroform: dichloromethane (1:2, v/v). In order to create a matrix with high porosity and uniform pore sizes, sieved sucrose crystals (300-500 mum) were used. PHBV foams we...
Bone response to biomimetic implants delivering BMP-2 and VEGF: An immunohistochemical study
RAMAZANOĞLU, Mustafa; Lutz, Rainer; Rusche, Philipp; Trabzon, Levent; Kose, Gamze Torun; Prechtl, Christopher; Schlegel, Karl Andreas (2013-12-01)
This animal study evaluated bone healing around titanium implant surfaces biomimetically coated with bone morphogenic protein-2 (BMP-2) and/or vascular endothelial growth factor (VEGF) by examining bone matrix proteins and mineralisation. Five different implant surfaces were established: acid-etched surface (AE), biomimetic calcium phosphate surface (CAP), BMP-2 loaded CAP surface, VEGF loaded CAP surface and dual BMP-2 + VEGF loaded CAP surface. The implants were inserted into calvariae of adult domestic p...
Bone tissue generation on biodegradable polymeric scaffolds
Torun Köse, Gamze; Hasırcı, Vasıf Nejat; Korkusuz, Feza; Department of Biotechnology (2002)
In the present study, tissue engineered bone was produced on calcium phosphate loaded collagen and PHBV8 matrices. Osteoblasts isolated from rat bone marrow were characterized by light microscopy, alkaline phosphatase (ALP) activity, osteocalcin determination assay, and Western blots for integrin. Population doubling time of the cells was found as 50 ± 2 h at 37 °C in a CO2 incubator. PHBV8 foams iiiwere treated with rf-oxygen plasma to modify their surface chemistry and hydrophilicity to increase the reatt...
Biomechanical and histological outcome of combined raloxifene-estrogen therapy on skeletal and reproductive tissues
Tasci, Arzu; BİLGİLİ, HASAN; Altunay, Hikmet; Gecit, Mehmet Rusen; Keskin, Dilek (Elsevier BV, 2010-02-10)
Estrogen replacement is a potent therapy for postmenopausal osteoporosis. However, its carcinogenic effects on breasts and the uterus limit its utilization. Raloxifene has estrogen-like effects on bones without the carcinogenic symptoms on breast or uterine tissue. Their individual effects are well characterized, but the results of their interaction remains elusive. In this work, we investigate the consequences of a combined raloxifene/estrogen therapy on bone and uterus with experimental osteoporosis. 40 W...
Archaeogenomic analysis of population genetic relationships and kinship patterns in the sedentary societies from neolithic anatolia
Yaka, Reyhan; Somel, Mehmet; Özer, Füsun; Department of Molecular Biology and Genetics (2020-1-12)
The Neolithic way of life first emerged in the Fertile Crescent (c.10thand early 9thmillennium cal BCE) and quickly spread to neighbouring regionssuch as Central Anatoliaand Cyprus,and eventually further westwards. This transition involved to fundamental changes in human lifestyle,with the first emergence of villages during the early Neolithicandthe later the growing reliance on farming and herdingduring the late Neolithic periods. Changes in the social organization of sedentary communi...
Citation Formats
T. GÜLTEKİN et al., “Bone mineral density of ancient Anatolian populations,” EKLEM HASTALIKLARI VE CERRAHISI-JOINT DISEASES AND RELATED SURGERY, pp. 133–139, 2008, Accessed: 00, 2020. [Online]. Available: