The immunological co-adjuvant action of liposomal interleukin-15



The expression of gst genes in diabetic rat liver tissues
İrtem Kartal, Deniz; Güray, Tülin; Department of Biochemistry (2008)
Free radicals which have critical roles in living systems through their beneficial and detrimental effects play an important role in medical revolution in health. Radicals are produced in the cells and tissues of our bodies by various processes and reactions. Diabetes mellitus is an extremely common disease in the world which seems to be accompanied by a shortage of antioxidants and an increase in free radicals, the end result of oxidative stress. Glutathione S-Transferases (GST; EC are found in e...
The expression of GST isoenzymes and p53 in non-small cell lung cancer.
Oguztßzun, Serpil; Aydin, Mehtap; Demirag, Funda; Yazici, Ulkß; Ozhavzali, Mßzeyyen; Kiliç, Murat; Can, Mesude IŠ(VM Media SP. zo.o VM Group SK, 2010-6-10)
This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase alpha, pi, mu, theta and p53 in non-small cell lung carcinoma and normal lung tissue from 50 patients. The relationships between expressions of the Glutathione-S-transferase isoenzymes and some clinicopathological features were also examined. Expression of glutathione-S-transferase pi, mu, alpha, theta and p53 was assessed by immunohistochemistry for primary lung carcinomas of 50 patients from the Sanitariu...
İşcan, Mesude; COBAN, T; EKE, BC; İşcan, Mesude (Springer Science and Business Media LLC, 1993-08-01)
When Cd (3.58 mg CdCl2 . H2O/kg, ip) was administered to male guinea pigs 72 h prior to sacrifice, the metal significantly inhibited the aniline 4-hydroxylase (AH) (16%), ethylmorphone N-demethylase (EMND) (26%), and aminopyrine N-demethylase (AMND) (18%) activities and cytochrome P-450 (12%) and cytochrome b5 (10%) levels. Cd did not alter the hepatic microsomal heme level. Cd, however, significantly increased the hepatic microsomal p-nitroanisole O-demethylase (p-NAOD) (53%) activity. When Ni (59.5 mg NiC...
The regulation of the CXXC5 gene expression
Yaşar, Pelin; Muyan, Mesut; Department of Molecular Biology and Genetics (2021-1-19)
17β-estradiol (E2) is the main circulating estrogen hormone in the body and is involved in the physiological and pathophysiological regulation of various tissue notably mammary tissue functions. E2 is responsible for cellular proliferation, differentiation, and/or death in target tissues. Our previous microarray studies suggested that expression of CXXC5 is regulated by E2-ERα through ERE-dependent signaling pathway and I verified that the CXXC5 transcript levels are augmented in response to E2. As a member...
The immunological co-adjuvant action of liposomal interleukin-2: The role of mode of localisation of the cytokine and antigen in the vesicles
Gürsel, Mayda (Informa UK Limited, 1998-01-01)
In experiments designed to study the co-adjuvant action of interleukin-2, a model antigen (tetanus toroid) was passively entrapped in, or covalently coupled to multilamellar liposomes in the presence or absence of interleukin-2 (IL-2). When present, IL-2 was either co-entrapped with the toroid, entrapped alone in liposomes with toroid coupled to their surface, or coupled to the surface of liposomes with entrapped toroid. The role of spatial localization of IL-2 within the liposomal structure (vis a vis that...
Citation Formats
M. Gürsel, “The immunological co-adjuvant action of liposomal interleukin-15,” 1997, vol. 293, Accessed: 00, 2020. [Online]. Available: