Bromination of norbornene derivatives: synthesis of brominated norbornanes and norbornenes

Date

2008-05-05

Author

Gueltekin, Demet Demirci
TAŞKESENLİGİL, Yavuz
DAŞTAN, Arif
Balcı, Metin

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The low and high temperature bromination of 7-bromobicyclo[2.2.1]hept-2-ene and 2,7-dibromobicyclo[2.2.1]hept-2-ene were studied and the possible role of a neighboring group participation in rearrangements was investigated. The formation mechanism of the isomers as well as the role of the substituent on the rearrangement were discussed. The structure elucidation of the formed compounds was achieved by NMR spectral data; particularly, the gamma-gauche effect was discussed in connection with the configuration of the bromine atoms.

Subject Keywords

Organic Chemistry, Biochemistry, Drug Discovery

URI

https://hdl.handle.net/11511/56985

Journal

TETRAHEDRON

DOI

https://doi.org/10.1016/j.tet.2008.02.067

Collections

Graduate School of Natural and Applied Sciences, Article

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Citation Formats

D. D. Gueltekin, Y. TAŞKESENLİGİL, A. DAŞTAN, and M. Balcı, “Bromination of norbornene derivatives: synthesis of brominated norbornanes and norbornenes,” TETRAHEDRON, pp. 4377–4383, 2008, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/56985.