Predictive accuracy of Southwest Thames Obstetric Research Collaborative (STORK) chorionicity-specific twin growth charts for stillbirth: a validation study

Kalafat, E.
Sebghati, M.
Thilaganathan, B.
Khalil, A.
Objective Twin pregnancy is associated with a 2-3-fold increased risk of stillbirth compared with singleton pregnancy. Despite the fact that the growth pattern in twins has been shown to be different from that in singletons, it is controversial whether twin-specific growth charts should be used routinely. A major goal of prenatal ultrasound is to identify fetuses with growth restriction at risk of stillbirth. The main aim of this study was to compare the performance of chorionicity-specific twin charts with singleton charts, both customized and non-customized, in the antenatal prediction of small-for-gestational-age (SGA) stillborn and liveborn fetuses.


Adverse neonatal outcome in twin pregnancy complicated by small-for-gestational age: twin vs singleton reference charts
Briffa, C.; Di Fabrizio, C.; Kalafat, Erkan; Giorgione, V.; Bhate, R.; Huddy, C.; Richards, J.; Shetty, S.; Khalil, A. (2022-03-01)
Objective The use of twin-specific vs singleton growth charts in the assessment of twin pregnancy has been controversial. The aim of this study was to assess whether a diagnosis of small-for-gestational age (SGA) made using twin-specific estimated-fetal-weight (EFW) and birth-weight (BW) charts is associated more strongly with adverse neonatal outcomes in twin pregnancies, compared with when the diagnosis is made using singleton charts.
Selective Fetal Growth Restriction in Dichorionic Twin Pregnancies: Diagnosis, Natural History, and Perinatal Outcome
Antonakopoulos, Nikolaos; Pateisky, Petra; Liu, Becky; Kalafat, Erkan; Thilaganathan, Baskaran; Khalil, Asma (MDPI AG, 2020-5-9)
This study aims to evaluate the natural history, disease progression, and outcomes in dichorionic twins with selective fetal growth restriction (sFGR) according to different diagnostic criteria and time of onset. Dichorionic twins seen from the first trimester were included. sFGR was classified according to the Delphi consensus, and was compared to the outcomes of those classified by the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) diagnostic criteria. Early sFGR occurred before ...
The Association Between Hypertension in Pregnancy and Preterm Birth with Fetal Growth Restriction in Singleton and Twin Pregnancy: Use of Twin Versus Singleton Charts
Kalafat, Erkan; Abiola, Aisha; Thilaganathan, Basky; Bhide, Amar; Khalil, Asma (MDPI AG, 2020-8-5)
Objective: To compare the rates of fetal growth restriction (FGR) in singleton and twin pregnancies using singleton and twin-specific birthweight standards. Methods: The study included liveborn twin and singleton pregnancies between January 2000 and January 2019. Hypertensive disorders of pregnancy (HDP) included gestational hypertension and pre-eclampsia. The study outcomes were FGR or small-for-gestational-age (SGA) at birth as assessed using singleton and twin reference charts. Results: The analysis incl...
Longitudinal change in cerebroplacental ratio in small-for-gestational-age fetuses and risk of stillbirth
Kalafat, E.; Ozturk, E.; Sivanathan, J.; Thilaganathan, B.; Khalil, A. (2019-10-01)
Objective To investigate whether assessment of longitudinal change in Doppler variables in small-for-gestational-age (SGA) fetuses improves the prediction of those at risk of stillbirth.
The outcome of the multifetal pregnancy reduction procedures in a single centre: A report of 202 completed cases
Yilanhoglu, Necip Cihangir; Semiz, Altug; Arisoy, Resul; Kahraman, Semra; Gurkan, Ali Arslan (Elsevier BV, 2018-11-01)
Objective: To review the results of fetal reduction procedures in our institution, evaluate its effects on the pregnancy outcome in terms of miscarriage, preterm delivery, taking home healthy babies and discuss the factors that may have contributed to the outcome.
Citation Formats
E. Kalafat, M. Sebghati, B. Thilaganathan, and A. Khalil, “Predictive accuracy of Southwest Thames Obstetric Research Collaborative (STORK) chorionicity-specific twin growth charts for stillbirth: a validation study,” ULTRASOUND IN OBSTETRICS & GYNECOLOGY, pp. 193–199, 2019, Accessed: 00, 2020. [Online]. Available: