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The Role of Apoptosis Regulator Programmed Cell Death 10 PDCD10 in Multidrug Resistance
Date
2015-06-20
Author
Çağrı, Urfalı Mamtoğlu
Gündüz, Ufuk
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https://hdl.handle.net/11511/75799
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Hepatocellular carcinoma (HCC) is projected to account for 4.7 percent of all new cancer cases and 8.2 percent of all cancer-related deaths globally. NADPH- dependent aldoketoreductases (AKRs) can reduce carbonyl substrates like glucose, sugar aldehydes, keto-steroids, keto-prostaglandins, retinals, quinones, and lipid peroxidation by-products. A member of this family of enzymes, AKR1B10, is thought to be a robust early marker for HCC as well as a predictor of poor prognosis. Oxidative stress in cells may r...
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U. M. Çağrı and U. Gündüz, “The Role of Apoptosis Regulator Programmed Cell Death 10 PDCD10 in Multidrug Resistance,” 2015, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/75799.