The Role of Apoptosis Regulator Programmed Cell Death 10 PDCD10 in Multidrug Resistance

Çağrı, Urfalı Mamtoğlu
Gündüz, Ufuk


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Hepatocellular carcinoma (HCC) is projected to account for 4.7 percent of all new cancer cases and 8.2 percent of all cancer-related deaths globally. NADPH- dependent aldoketoreductases (AKRs) can reduce carbonyl substrates like glucose, sugar aldehydes, keto-steroids, keto-prostaglandins, retinals, quinones, and lipid peroxidation by-products. A member of this family of enzymes, AKR1B10, is thought to be a robust early marker for HCC as well as a predictor of poor prognosis. Oxidative stress in cells may r...
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The Role of NEK6 gene expression in multidrug resistance and apoptosis in MCF-7 and K-562 cell lines
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Grey mold disease is one of these postharvest decays. Especially grapes are infected by Botrytis cinerea known as a causal agent of the grey mold disease. Some fungicides are used to control this disease. However, they cause funcide- resistant strains of the pathogens and make hazardous for human health and environmental safety. Therefore, The killer yeasts are considered as promising alternative antifungal agents among other biocontrol agents. Pichia anomala which is a killer yeast secretes the K5 type yea...
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Citation Formats
U. M. Çağrı and U. Gündüz, “The Role of Apoptosis Regulator Programmed Cell Death 10 PDCD10 in Multidrug Resistance,” 2015, Accessed: 00, 2021. [Online]. Available: