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Untargeted metabolomic andlipidomic characterization of brain tissue using solid phase microextraction
Date
2017-06-04
Author
Boyacı, Ezel
Gómez-ríos, German A
Bojko, Barbara
Pawliszyn, Janusz
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https://www.asms.org/docs/default-source/asms-2017/65thasms-program_full_web_v2.pdf?sfvrsn=0
https://hdl.handle.net/11511/77679
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Untargeted analysis of brain tissue using solid phase microextraction
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Untargeted metabolomics profiling of skeletal muscle samples from malignant hyperthermia susceptible patients
Bojko, Barbara; Vasiljevic, Tijana; Boyacı, Ezel; Roszkowska, Anna; Kraeva, Natalia; Moreno, Carlos A. Ibarra; Koivu, Annabel; Wasowicz, Marcin; Hanna, Amy; Hamilton, Susan; Riazi, Sheila; Pawliszyn, Janusz (Springer Science and Business Media LLC, 2021-01-01)
Purpose Malignant hyperthermia (MH) is a potentially fatal hypermetabolic condition triggered by certain anesthetics and caused by defective calcium homeostasis in skeletal muscle cells. Recent evidence has revealed impairment of various biochemical pathways in MH-susceptible patients in the absence of anesthetics. We hypothesized that clinical differences between MH-susceptible and control individuals are reflected in measurable differences in myoplasmic metabolites. Methods We performed metabolomic profil...
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E. Boyacı, G. A. Gómez-ríos, B. Bojko, and J. Pawliszyn, “Untargeted metabolomic andlipidomic characterization of brain tissue using solid phase microextraction,” 2017, Accessed: 00, 2021. [Online]. Available: https://www.asms.org/docs/default-source/asms-2017/65thasms-program_full_web_v2.pdf?sfvrsn=0.