Label-free Multidrug Resistance Detection in MCF-7 Cells by Isolated 3D-Electrode Dielectrophoresis

Date

2014-07-16

Author

Demircan Yalçın, Yağmur
Erdem, Murat
Özgür, Ebru
Gündüz, Ufuk
Külah, Haluk

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https://hdl.handle.net/11511/81603

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Label-free enrichment of MCF7 breast cancer cells from leukocytes using continuous flow dielectrophoresis Arslan, Zeynep Caglayan; Yalcin, Yagmur Demircan; Külah, Haluk (2022-04-01) Circulating tumor cells (CTCs) present in the bloodstream are strongly linked to the invasive behavior of cancer; therefore, their detection holds great significance for monitoring disease progression. Currently available CTC isolation tools are often based on tumor-specific antigen or cell size approaches. However, these techniques are limited due to the lack of a unique and universal marker for CTCs, and the overlapping size between CTCs and regular blood cells. Dielectrophoresis (DEP), governed by the in...
Label-free detection of telomerase activity using guanine electrochemical oxidation signal Eskiocak, Ugur; Ozkan-Ariksoysal, Dilsat; Ozsoz, Mehmet; Öktem, Hüseyin Avni (American Chemical Society (ACS), 2007-11-15) Telomerase is an important biomarker for cancer cells and its activation in 85% of all cancer types confers a clinical diagnostic value. A label-free electrochemical assay based on guanine oxidation signal to measure telomerase activity is described. This developed technology combined with a disposable sensor, carbon graphite electrode (CGE), and differential pulse voltammetry (DPV) was performed by using PCR amplicons with/without telomeric repeats as the guanine oxidation signal observed at +1.0 V measure...
Label-Free DNA Detection Using a Charge Sensitive CMOS Microarray Sensor Chip Musayev, Javid; Adlguzel, Yekbun; KÜLAH, HALUK; Eminoglu, Selim; Akın, Tayfun (Institute of Electrical and Electronics Engineers (IEEE), 2014-05-01) This paper presents label-free DNA detection using a charge sensitive microarray sensor. The microarray sensor, fabricated with a standard CMOS process, contains 1024 detector elements integrated together with their readout circuit in a single chip. This microarray sensor chip is developed for biosensing applications involving label-free detection of charged particles and molecules with improved sensitivity. The proposed chip is used for the detection of DNA immobilization and hybridization by directly sens...

Citation Formats

Y. Demircan Yalçın, M. Erdem, E. Özgür, U. Gündüz, and H. Külah, “Label-free Multidrug Resistance Detection in MCF-7 Cells by Isolated 3D-Electrode Dielectrophoresis,” 2014, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/81603.