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Lab on a chip: A versatile integration with spectroscopic techniques
Date
2020-08-01
Author
Eryılmaz, Merve
Yıldırım, Ender
Tamer, Uğur
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In the field of biomolecule detection, there are many conventional methods; however, there is a demand for applications that are more sensitive, accurate, and capable of analyzing small sample volumes. Lab-on-a-chip (LOC) devices are promising multifunctional tools for these purposes and the combination of LOC with spectroscopy provides rapid and reliable biomolecule detection. In the LOC system, a high number of analytes can be also detected simultaneously and LOC devices are preferred for both labeled and label-free detection of protein, DNA, cells, and bacteria. Raman spectroscopy and fluorescence spectroscopy have advantages for biomolecules among the other spectroscopic techniques and this chapter is focused on their analytical applications in LOC devices.
Subject Keywords
Lab-on-a-chip
,
Spectroscopy
,
Raman
,
Fluorescence
,
SERS
,
Biomolecule detection
URI
https://www.sciencedirect.com/science/article/pii/B9780128197639000076
https://hdl.handle.net/11511/82882
Relation
Handbook on Miniaturization in Analytical Chemistry
Collections
Department of Mechanical Engineering, Book / Book chapter
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M. Eryılmaz, E. Yıldırım, and U. Tamer,
Lab on a chip: A versatile integration with spectroscopic techniques
. 2020, p. 152.