15th International Symposium on Health Informatics and Bioinformatics HIBIT’22 (20-22 October 2022)

Date of Issue

2022-10

Publisher

Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü

URI

http://hibit2022.ims.metu.edu.tr
https://hdl.handle.net/11511/101298

Editor

Aydın Son, Yeşim
Karahan, Arzu
Otlu, Burçak

Conference Name

The International Symposium on Health Informatics and Bioinformatics

Conference Location

Erdemli, Mersin, TÜRKİYE

Metadata

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Papers

HIBIT Proceedings 2022 Aydın Son, Yeşim; Karahan, Arzu; Otlu Sarıtaş, Burçak (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10) ABOUT HIBIT The International Symposium on Health Informatics and Bioinformatics (HIBIT), first held in 2005, aims to bring together academics, researchers, and practitioners who work in these popular and fulfilling are...
Computational design of a genetically encoded iron biosensor Berksöz, Melike; Atılgan, Canan (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10) Genetically encoded fluorescent biosensors (GEFB) proved to be reliable tracers for many metabolites and cellular processes. In the simplest case, a fluorescent protein (FP) is genetically fused to a sensing protein which ...
Probing the structural impacts of arg388 replacements in pkp2 protein complex: spesific case in arvc Kutlu, Aslı; Şahin, Şuara; Özkan, Mehmet Emre; Ulukaya, Engin (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10) In this study, we aimed to probe the roles of missense variants in PKP2 protein structures in ARVC-related clinics. Within the structure of PKP2 protein, there were many missense var-iants, whose associations with ARVC we...
Impact of imputation on the cell type identification in scrna-seq datasets Avşar, Gülben; Pir, Pınar (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10) Single-cell RNA sequencing technologies allow investigation of the cellular heterogeneity and processes in high resolution. However, the technical limitations and biological factors give rise to challenges in the analyses ...
PROT-ON: Structure-Based Detection of Critical Mutations in Redesigning Protein-Protein Interfaces Koşaca, Mehdi; Yılmazbilek, İrem; Karaca , Ezgi (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10) Deformation of protein-protein interactions (PPIs) causes several diseases. Many therapeutic agents have been developed by time-consuming experimental techniques. On the other hand, computational methods have been used to ...
Allosteric changes in the centromere-specific nucleosome in response to physical factors Önder, Onur; Boopathi, Ramachandran; Angelov, Dimitar; Dimitrov, Stefan; Kale, Seyit (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10) Faithful segregation of sister chromatids is critical for the transfer of genetic inheritance during cell division. This is accomplished through the physical separation of these chromatids to the opposite cell poles via th...
Investigation of Effects of Microenvironment and Immune Cells onTumor Growth by Agent Based Modeling Orta Doğu Teknik Üniversitesi, Deniz Bilimleri Enstitüsü (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10) Cancer is one of the diseases that humanity suffered for a long time. We understand many aspects of this disease, but there is still much to learn. Because it is a complex disease that affects many processes, organs, cell ...
A novel phylogeny-dependent coevolution algorithm Kuru, Nurdan; Adebali, Ogün (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10)
Assessment of machine-learning- versus experimental structural models of sex-specific isoforms of linker histone H1 Uça, Merve; Dimitrov, Stefan; Kale, Seyit (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10) The nucleosome is the repeating unit of chromatin and it is composed of an octamer histone core that holds together around 145 base pairs of DNA in a disc-shaped configuration. In higher eukaryotes, an additional histone, ...
Reproducible and scalable data analysis on high performance computing Akkoyun, Emrah; Kuru, Nurdan; Dereli, Onur; Bircan, Aylin; Taştan, Öznur; Adebali, Ogün (Orta Doğu Teknik Üniversitesi Enformatik Enstitüsü; 2022-10) We recently presented the PHACT tool ( PHylogeny-Aware Computation of Tolerance) for assessing amino acid substitutions that achieved superior predictive performance compared to widely adapted tools [1]. PHACT scores alter...

Citation Formats

“15th International Symposium on Health Informatics and Bioinformatics HIBIT’22 (20-22 October 2022),” 00, 2022, Accessed: 00, 2023. [Online]. Available: http://hibit2022.ims.metu.edu.tr.