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Network-based in silico modeling for drug repurposing and in vitro validation in hepatocellular carcinoma
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HIBIT22_paper_104.pdf
Date
2022-10
Author
Nalbat, Esra
Tunçbağ, Nurcan
Cetin-Atalay, Rengul
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Hepatocellular carcinoma (HCC) is the sixth most commonly diagnosed cancer and a leading cause of death worldwide. The hyperactivated cell survival signaling pathways cause resistance to conventional chemotherapeutics so that targeted therapies could extend patient survival for only a few months. Furthermore, there are limited chemotherapeutics for HCC patients due to impaired liver functions. Thus, it is vital to determine repurposed drugs and drug combinations in HCC treatment.
URI
https://hibit2022.ims.metu.edu.tr
https://hdl.handle.net/11511/101356
Conference Name
The International Symposium on Health Informatics and Bioinformatics
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Graduate School of Informatics, Conference / Seminar
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E. Nalbat, N. Tunçbağ, and R. Cetin-Atalay, “Network-based in silico modeling for drug repurposing and in vitro validation in hepatocellular carcinoma,” Erdemli, Mersin, TÜRKİYE, 2022, p. 3104, Accessed: 00, 2023. [Online]. Available: https://hibit2022.ims.metu.edu.tr.