Show/Hide Menu
Hide/Show Apps
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Open Access Guideline
Open Access Guideline
Postgraduate Thesis Guideline
Postgraduate Thesis Guideline
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Guides
Guides
Thesis submission
Thesis submission
MS without thesis term project submission
MS without thesis term project submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Supporting Information
Supporting Information
General Information
General Information
Copyright, Embargo and License
Copyright, Embargo and License
Contact us
Contact us
Early Postoperative Adjuvant Radiotherapy Versus Active Monitoring After Gross Total Resection for Atypical Meningiomas: Factors Associated with Early Recurrence
Date
2023-01-01
Author
GÜRSES, MUHAMMET ENES
ZENGİN, HATİCE YAĞMUR
Shikhaliyeva, Aysel
Aşkun, Cengiz Savaş
Mut, Melike
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
108
views
0
downloads
Cite This
AIM: To investigate the predictors of recurrence after gross total resection (GTR) that require early adjuvant radiotherapy upfront rather than at initial recurrence of atypical meningiomas (AMs). MATERIAL and METHODS: A retrospective study of gross totally resected AMs was conducted in a tertiary care center within ten years. The clinical, radiological, and pathological parameters were analyzed statistically, and the factors associated with recurrence after GTR were determined with univariate analysis. RESULTS: Among 23 AMs with GTR, 34.8% showed recurrence in a median follow-up of 40 months after the surgery. Preoperative tumor volume, tumor location in the skull base or tentorium, and lack of progesterone expression were associated with the higher recurrence rate. AMs with a preoperative volume of 27.5 cm3 were the most significant risk factor for the recurrence (a 9.3-fold increase) than those with 27.5 cm3) might have higher recurrence rates after GTR and, therefore, would benefit from early adjuvant radiotherapy without waiting for a recurrence. AMs located in the skull base or tentorium and AMs having no progesterone expression might also be potential predictors for recurrence.
Subject Keywords
Atypical
,
Meningioma
,
Radiotherapy
,
Recurrence
,
Resection
URI
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85166165172&origin=inward
https://hdl.handle.net/11511/104927
Journal
Turkish Neurosurgery
DOI
https://doi.org/10.5137/1019-5149.jtn.41369-22.1
Collections
Department of Computer Education and Instructional Technology, Article
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
M. E. GÜRSES, H. Y. ZENGİN, A. Shikhaliyeva, C. S. Aşkun, and M. Mut, “Early Postoperative Adjuvant Radiotherapy Versus Active Monitoring After Gross Total Resection for Atypical Meningiomas: Factors Associated with Early Recurrence,”
Turkish Neurosurgery
, vol. 33, no. 4, pp. 635–641, 2023, Accessed: 00, 2023. [Online]. Available: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85166165172&origin=inward.