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Biocompatible Janus microparticle synthesis in a microfluidic device
Date
2024-09-01
Author
Saqib, Muhammad
Tufan, Yiğithan
Orsel, Z. Cemre
Ercan, Batur
Erdem, E. Yegan
Metadata
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Janus particles are popular in recent years due to their anisotropic physical and chemical properties. Even though there are several established synthesis methods for Janus particles, microfluidics-based methods are convenient and reliable due to low reagent consumption, monodispersity of the resultant particles and efficient control over reaction conditions. In this work a simple droplet-based microfluidic technique is utilized to synthesize magnetically anisotropic TiO2-Fe2O3 Janus microparticles. Two droplets containing reagents for Janus particle were merged by using an asymmetric device such that the resulting droplet contained the constituents within its two hemispheres distinct from each other. The synthesized Janus particles were observed under the optical microscope and the scanning electron microscope. Moreover, a detailed in vitro characterization of these particles was completed, and it was shown that these particles have a potential use for biomedical applications.
Subject Keywords
Biocompatible particles
,
Droplet based flow
,
Janus particles
,
Microfluidics
,
Microreactors
URI
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85197241034&origin=inward
https://hdl.handle.net/11511/110278
Journal
Biomedical Microdevices
DOI
https://doi.org/10.1007/s10544-024-00711-4
Collections
Department of Metallurgical and Materials Engineering, Article
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BibTeX
M. Saqib, Y. Tufan, Z. C. Orsel, B. Ercan, and E. Y. Erdem, “Biocompatible Janus microparticle synthesis in a microfluidic device,”
Biomedical Microdevices
, vol. 26, no. 3, pp. 0–0, 2024, Accessed: 00, 2024. [Online]. Available: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85197241034&origin=inward.