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READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics
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READv2-advanced and user-friendly.pdf
Date
2024-12-01
Author
Alaçamlı, Erkin
Naidoo, Thijessen
Güler, Murat
Sağlıcan, Ekin
Aktürk, Şevval
Mapelli, Igor
Vural, Kıvılcım Başak
Somel, Mehmet
Malmström, Helena
Günther, Torsten
Metadata
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
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The advent of genome-wide ancient DNA analysis has revolutionized our understanding of prehistoric societies. However, studying biological relatedness in these groups requires tailored approaches due to the challenges of analyzing ancient DNA. READv2, an optimized Python3 implementation of the most widely used tool for this purpose, addresses these challenges while surpassing its predecessor in speed and accuracy. For sufficient amounts of data, it can classify up to third-degree relatedness and differentiate between the two types of first-degree relatedness, full siblings and parent-offspring. READv2 enables user-friendly, efficient, and nuanced analysis of biological relatedness, facilitating a deeper understanding of past social structures.
Subject Keywords
Ancient DNA
,
Archaeogenomics
,
Kinship
,
Relatedness
,
Software
URI
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85201252750&origin=inward
https://hdl.handle.net/11511/111144
Journal
Genome Biology
DOI
https://doi.org/10.1186/s13059-024-03350-3
Collections
Department of Civil Engineering, Article
Citation Formats
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MLA
BibTeX
E. Alaçamlı et al., “READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics,”
Genome Biology
, vol. 25, no. 1, pp. 0–0, 2024, Accessed: 00, 2024. [Online]. Available: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85201252750&origin=inward.