READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics

2024-12-01
Alaçamlı, Erkin
Naidoo, Thijessen
Güler, Murat
Sağlıcan, Ekin
Aktürk, Şevval
Mapelli, Igor
Vural, Kıvılcım Başak
Somel, Mehmet
Malmström, Helena
Günther, Torsten
The advent of genome-wide ancient DNA analysis has revolutionized our understanding of prehistoric societies. However, studying biological relatedness in these groups requires tailored approaches due to the challenges of analyzing ancient DNA. READv2, an optimized Python3 implementation of the most widely used tool for this purpose, addresses these challenges while surpassing its predecessor in speed and accuracy. For sufficient amounts of data, it can classify up to third-degree relatedness and differentiate between the two types of first-degree relatedness, full siblings and parent-offspring. READv2 enables user-friendly, efficient, and nuanced analysis of biological relatedness, facilitating a deeper understanding of past social structures.
Genome Biology
Citation Formats
E. Alaçamlı et al., “READv2: advanced and user-friendly detection of biological relatedness in archaeogenomics,” Genome Biology, vol. 25, no. 1, pp. 0–0, 2024, Accessed: 00, 2024. [Online]. Available: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85201252750&origin=inward.