Synthesis of bioactive products from polyketide intermediates.

1984
Altınok, Altan
Show full item record
101
views
0
downloads
Heterocyclic compounds., Promotic compounds.
https://hdl.handle.net/11511/11741
Graduate School of Natural and Applied Sciences, Thesis

Suggestions

Synthesis of highly substituted alkynylpyridines and development of new methodologies for the synthesis of 1,4-oxazepines, 1,4-thiazepines and 5-methylpyridines /
Kelgökmen, Yılmaz; Zora, Metin; Department of Chemistry (2018)
Convenient syntheses of pyridines, 1,4-oxazepines and 1,4-thiazepines have become an important research area among organic chemists since they constitute scaffolds of many medicinal substances. Recently, N-propargylic β-enaminones have been widely used for the facile synthesis of potent biologically active heterocycles. Many research groups have focused on the proper synthesis of various heterocycles by using N-propargylic β-enaminones. One of the such recent reports using these precursors is the formation ...
Synthesis of 6-halogen-substituted 2-methylene-2,3dihydro-1,4-oxazepine derivatives
İbiş, Özge; Zora, Metin; Department of Chemistry (2017)
Heterocyclic compounds are important since they are present in life naturally or synthetically. Among heterocyclic compounds, seven-membered 1,4-oxazepines are giving more attention than ever due to their wide range of biological and medicinal activities. There are many studies about their synthesis and new ones continue to appear. In this study, synthesis of halogen-substituted 1,4-oxazepine derivatives was investigated, which may have potential for biological studies. For this purpose, α,β-alkynic ketone ...
Synthesis of alkynyl-substituted pyrrole and 1,4-thiazepine derivatives
Yılmaz, Elif Serel; Zora, Metin; Department of Chemistry (2018)
Heterocyclic compounds have a great importance in medicinal chemistry because of their presence in a number of pharmaceuticals. Among them, pyrroles and 1,4-thiazepines play a vital role in pharmaceutical chemistry because of their presence in a number of bioactive molecules and natural products. For this reason, the development of new synthetic methods for the synthesis of these compounds has attracted much attention. Recently, the cyclization of functionally-substituted alkynes has emerged as a valuable t...
Synthesis and electrochemical studies of fluorene and benzimidazole containing conjugated polymers
Namal, İmge; Toppare, Levent Kamil; Arslan Udum, Yasemin; Department of Chemistry (2013)
The synthesis and characterization of two donor acceptor type conjugated polymers were investigated. The electrochemical properties were examined using cyclic voltammetry, spectroelectrochemistry and kinetic studies. The increase in the alkyl chain length attached to the fluorene unit was investigated by the corresponding electrochemical characteristics. The synthesis was carried out via Stille coupling of 4,7- dibromo-4'-(tert-butyl)spiro[benzo[d]imidazole-2,1' cyclohexane] and 2,5- bis(tributylstannyl)thi...
Investigation of organic radical reaction mechanism of various 5-membered heterocyclics with OHand SOin aqueous solution by the use of ESR and pulse radiolysis methods.
Doğan, İlknur; İçli, Sıddık; Department of Chemistry (1984)
Citation Formats
A. Altınok, “Synthesis of bioactive products from polyketide intermediates.,” Ph.D. - Doctoral Program, Middle East Technical University, 1984.
METU IIS - Integrated Information Service open@metu.edu.tr