Intermolecular addition of aldehydes to ketones via acyl phosphonates

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2008

Author

Esiringü, İlker

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This thesis presents a new developed method for first intermolecular aldehyde/ketone cross benzoin coupling. Protected α-keto tertiary alcohols are synthesized starting from easily available acyl phosphonates and ketones via Brook rearrangement in the presence of catalytic amount of cyanide ion. The scopes and the limitations of the methods for the synthesis of tertiary alcohols with α-keto group are discovered.

Subject Keywords

Chemistry., Chemistry, Organic

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http://etd.lib.metu.edu.tr/upload/3/12609441/index.pdf
https://hdl.handle.net/11511/17640

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Graduate School of Natural and Applied Sciences, Thesis

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Citation Formats

İ. Esiringü, “Intermolecular addition of aldehydes to ketones via acyl phosphonates,” M.S. - Master of Science, Middle East Technical University, 2008.