Development of acyl anion precursors and their applications

Download

index.pdf

Date

2005

Author

Reis, Ömer

Metadata

Show full item record

Item Usage Stats

234
views

95
downloads

This thesis presents the development of new acyl anion precursors and their applications. The main concern of this thesis was to make use of acyl anion precursors in catalytic bond forming reactions. Toward this aim, previously known cyanide ion catalyzed cleavage of benzils was investigated in scope and efficiency in unsymmetrical benzoin condensation. Although benzils were proved to be useful entities as acyl anion precursors in benzoin condensation, they suffer some major drawbacks. Therefore acylphosphonates were proposed and investigated as a new generation of acyl anion precursor. They were found to be highly versatile and efficient in both catalytic unsymmetrical benzoin synthesis and other useful transformations.

Subject Keywords

Chemistry, Organic

URI

http://etd.lib.metu.edu.tr/upload/3/12605950/index.pdf
https://hdl.handle.net/11511/14968

Collections

Graduate School of Natural and Applied Sciences, Thesis

Suggestions

OpenMETU
Core

Synthesis and reactions of alpha-keto-beta-hydroxyphosphonates Barış, Şehriban; Demir, Ayhan Sıtkı; Department of Chemistry (2007) This thesis presents synthesis and different reactions of alpha-keto-beta-hydroxyphosphonates. Toward this aim, the hydroxyl functionality of alpha-hydroxycarboxylic acids were protected with alkyl or acyl groups and then formation of acid chloride followed by the reaction with trialkylphosphite furnished protected alpha-keto-beta-hydroxyphosponates. Nucleophilic addition reactions were applied to these compounds to obtain quaternary alcohols with phosphonate functionality. The addition reactions were tried...
Synthesis and enzymatic resolution of various cyclopentenoid and cyclohexenoid type compounds İyigün, Çiğdem; Tanyeli, Cihangir; Department of Chemistry (2005) The aim of this thesis is to synthesize enantiomerically enriched cyclopentenoid and cyclohexenoid type of compounds with quaternary carbon stereocenters that are the simplest precursors of the complex natural products. The first part of the study involves the preparation of ?'-acetoxy ?'-substituted ?,β-unsaturated cyclic ketones. Methylation, ethylation, benzylation and allylation of cyclohexenone and cyclopentenone derivatives are performed. Then, these compounds are regioselectively oxidized at the ?'-p...
Structural analysis of polyaniline-polyprrole copolmers via pyrolysis mass spectrometry Tezal, Feride; Küçükyavuz, Zuhal; Department of Chemistry (2007) This thesis describes recent progress in electrochemical preparation of several conducting polymers. In particular, the synthesis and characterizations of pure polyaniline, pure polypyrrole, polyaniline/polypyrrole and polypyrrole/polyaniline copolymers and polyaniline-polypyrrole physical blends were studied. The focus has included firstly synthesis of these electrically conductive polymers. Secondly, thermal characteristics of electrochemically synthesized homopoly- mers, copolymers and their physical ble...
Novel studies on the chemoenzymatic synthesis of polychlorinated bicyclic systems and the synthesis of C2 and C3 symmetric chiral ligands Türkmen, Yunus Emre; Tanyeli, Cihangir; Department of Chemistry (2006) Optically active polychlorinated bicyclic systems are important starting materials for the synthesis of complex target molecules. In the first part of the study, the syntheses of several racemic and meso hexachloronorbornene derivatives were executed successfully, starting from hexachlorocyclopentadiene. The enantio-enriched acetoxymethyl derivative (-)-2 and the hemiester (-)-6 were synthesized in high e.e. values by using several hydrolase type enzymes. The absolute configuration of (-)-2 was determined b...
Activity of carbon supported platinum nanoparticles catalysts toward methanol oxidation reaction : role of metal precursor and a new surfactant Şen, Selda; Gökağaç Arslan, Gülsün; Department of Chemistry (2008) In this thesis, carbon supported platinum nanoparticle catalysts were prepared using PtCl4 and H2PtCl6 as starting materials and 1-heptanethiol, tert-nonyl mercaptan, 1-hexadecanethiol, 1-octadecanethiol as surfactants. These new catalysts were employed for methanol oxidation reaction which are used for direct methanol fuel cells. Tert-nonyl mercaptane was used for the first time in this type of reaction and the other surfactants were used for comparison of the catalysts performance. Cyclic voltammetry (CV)...

Citation Formats

Ö. Reis, “Development of acyl anion precursors and their applications,” Ph.D. - Doctoral Program, Middle East Technical University, 2005.