Development of acyl anion precursors and their applications

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2005

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Reis, Ömer

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This thesis presents the development of new acyl anion precursors and their applications. The main concern of this thesis was to make use of acyl anion precursors in catalytic bond forming reactions. Toward this aim, previously known cyanide ion catalyzed cleavage of benzils was investigated in scope and efficiency in unsymmetrical benzoin condensation. Although benzils were proved to be useful entities as acyl anion precursors in benzoin condensation, they suffer some major drawbacks. Therefore acylphosphonates were proposed and investigated as a new generation of acyl anion precursor. They were found to be highly versatile and efficient in both catalytic unsymmetrical benzoin synthesis and other useful transformations.

Subject Keywords

Chemistry, Organic

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http://etd.lib.metu.edu.tr/upload/3/12605950/index.pdf
https://hdl.handle.net/11511/14968

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Graduate School of Natural and Applied Sciences, Thesis

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Citation Formats

Ö. Reis, “Development of acyl anion precursors and their applications,” Ph.D. - Doctoral Program, Middle East Technical University, 2005.