Catalytic asymmetric nitroaldol (Henry) reaction with a zinc-Fam catalyst

Date

2008-09-19

Author

Bulut, Adnan
Aslan, Ayhan
Doğan, Özdemir

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Ferrocenyl-substituted aziridinylmethanol (Fam-1) was used as a catalyst with zinc for the asymmetric nitroaldol (Henry) reaction. This catalyst worked with a variety of aldehydes (aromatic, aliphatic, alpha,beta-unsaturated, and heteroaromatic) and alpha-ketoesters to give the nitroaldol product in up to 97% yield and 91% ee. The chiral ligand call be recovered and recycled Without losing its activity.

Subject Keywords

Organic Chemistry

URI

https://hdl.handle.net/11511/46471

Journal

JOURNAL OF ORGANIC CHEMISTRY

DOI

https://doi.org/10.1021/jo8010073

Collections

Department of Chemistry, Article

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Citation Formats

A. Bulut, A. Aslan, and Ö. Doğan, “Catalytic asymmetric nitroaldol (Henry) reaction with a zinc-Fam catalyst,” JOURNAL OF ORGANIC CHEMISTRY, pp. 7373–7375, 2008, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/46471.