An Extensible security infrastructure for the secondary use of electronic health records in clinical research

Download

index.pdf

Date

2013

Author

Eryılmaz, Elif

Metadata

Show full item record

Item Usage Stats

232
views

110
downloads

In order to facilitate clinical research studies re-using Electronic Health Records (EHR) has a great potential. Besides interoperability, safeguarding the security and privacy of the medical data in the context of secondary use for clinical research is one of the most important challenges in this respect. In order to ensure that the clinical information is shared among EHR systems and clinical research systems in an ethical and safe way, there needs to be standards-based and adaptable security and privacy mechanisms that can be used by both clinical care and clinical research parties in an interoperable manner by taking into account policies, consent and use agreements of the participating parties. In this thesis, an extensible security infrastructure has been developed that supports re-use of the EHRs for strengthening the post-approval drug safety studies in the area of clinical research. This work involves the implementation of the security architecture, including novel data protection mechanisms applied to the queried clinical instances as well as additional security services compatible with standard profiles that guarantees the safe use of EHRs for the clinical research studies. In conformance to the selected standards, guidelines, and well-accepted methodologies, this thesis has addressed to find a balance between the privacy concerns for the use of personal data and the requirements of clinical research environments that aim to serve to the public good. In this respect, flexible security architecture is designed and made configurable for the Data Protection Offices of EHR sources according to their preferences.

Subject Keywords

Medical records, Medical records, Medical archives, Information storage and retrieval systems, Medical informatics

URI

http://etd.lib.metu.edu.tr/upload/12616003/index.pdf
https://hdl.handle.net/11511/22694

Collections

Graduate School of Natural and Applied Sciences, Thesis

Suggestions

OpenMETU
Core

Evaluation of an electronic medical record system : Zonguldak Karaelmas University Hospital survey Uğurbaş, Suat Hayri; Erdil, Erkan; Department of Science and Technology Policy Studies (2006) The present study investigated the electronic medical record system (EMR) of Zonguldak Karaelmas University Hospital which is used for six years now. The advantages and disadvantages of an EMR system in comparison with paper medical records were evaluated based on the user’s opinion. The recommendations for the development of EMR and more efficient use of the system are principle goals of this study. The purposes of this thesis include promoting the implantation of EMR by introducing the advantages and disa...
An Advanced personal health record platform for patient empowerment Postacı, Şenan; Çiçekli Kesim, Nihan; Doğaç, Asuman; Department of Computer Engineering (2012) In recent years, many Personal Health Record (PHR) systems have been developed to retrieve patients’ Electonic Health Records (EHRs) from external sources. However, current PHRs can provide access to only a small number of EHR systems, since there are many di erent interfaces, data formats and medical terminologies among di erent systems. When this is the case, all these diversity yields high integration costs. Development of such systems is di cult and expensive because of the reasons such as accessing to ...
A Multi-layer model for privacy preserving policy making for disclosure of public health data Alizadeh Mizani, Mehrdad; Baykal, Nazife; Department of Medical Informatics (2013) Health organizations in Turkey collect ever-increasing amount of individual data are valuable source of information for public health research. However, due to privacy risks, they publish data in aggregated rather than individual forms. The lack of standardized policies regarding secondary uses of health data leads to ineffectiveness of available technical methods. As a result, access to and utilization of person-specific datasets by public health researchers become extremely cumbersome. The bias introduced...
A Semantic interoperability framework for reinforcing post market safety studies Yüksel, Mustafa; Coşar, Ahmet; Department of Computer Engineering (2013) Depending mostly on voluntarily sent spontaneous reports, pharmacovigilance studies are hampered by low quantity and quality of patient data. Enabling safety analysts to seamlessly access a wide range of Electronic Health Record (EHR) sources for collecting de-identified medical data sets of selected patient populations and tracing the reported incidents back to original EHRs can provide major improvements for such post market safety studies. The adoption of EHR systems and data exchange among these systems...
Semantic transformation framework to enable statistical research on medical summaries Paçacı, Anıl; Altıngövde, İsmail Sengör; Doğaç, Asuman; Department of Computer Engineering (2015) One of the important aspects of the clinical research studies carried out in the pharmacovigilance and pharmacoepidemiology is the postmarketing drug surveillance. Utilization of the available Electronic Health Record (EHR) data is key to complement and strengthen the postmarketing safety studies. In addition, EHRs provide a huge, but still under-utilized source of information for the observational studies in clinical research. However, use of different EHR data models and vocabularies presents an important...

Citation Formats

E. Eryılmaz, “An Extensible security infrastructure for the secondary use of electronic health records in clinical research,” M.S. - Master of Science, Middle East Technical University, 2013.