E-mail
dengizc@metu.edu.tr
Department
Department of Chemistry
Scopus Author ID
Web of Science Researcher ID
Crystal structure determination and computational studies of 1,4-dihydropyridine derivatives as selective T-type calcium channel blockers
GÜNDÜZ, MİYASE GÖZDE; Armakovic, Sanja J.; Dengiz, Çağatay; Tahir, Muhammad Nawaz; Armakovic, Stevan (2021-04-01)
Different types of calcium channels are crucial regulators of many key physiological functions throughout the body. Therefore, calcium channel modulators are accepted as precious molecules for the therapeutic intervention ...
Iron-Catalyzed α-C-H Cyanation of Simple and Complex Tertiary Amines.
Yilmaz, Ozgur; Dengiz, Çağatay; Emmert, Marion H (American Chemical Society (ACS), 2021-01-19)
This manuscript details the development of a general and mild protocol for the α-C–H cyanation of tertiary amines and its application in late-stage functionalization. Suitable substrates include tertiary aliphatic, benzyli...
Synthesis, characterization, and theoretical investigation of optical and nonlinear optical (NLO) properties of triazene-based push–pull chromophores
Mammadova, Flora; Ozsinan, Semin; Okutan, Merve; Dengiz, Çağatay (Elsevier BV, 2020-11-15)
A short and efficient synthetic strategy for the synthesis of triazene-substituted push–pull dyes has been developed. The formal [2 + 2] cycloaddition-retroelectrocyclization was utilized for the preparation of the target ...
Synthesis of thienopyridinones via hydrazide-alkyne cyclization
Cokol, Nalan Korkmaz; Erden, Kübra; Gunay, Furkan Melih; Dengiz, Çağatay; Balci, Metin (Elsevier BV, 2020-05-08)
A novel and efficient method for the synthesis of thieno[3,2-c]pyridinones have been developed. The synthetic strategy relies on the synthesis of halothiophene esters utilized as substrates for subsequent Sonogashira cross...
Bioproduction, structure elucidation and in vitro antiproliferative effect of eumelanin pigment from Streptomyces parvus BSB49
Bayram, Sinan; Dengiz, Çağatay; GERÇEK, Yusuf Can; ÇETİN, İdil; TOPÇUL, Mehmet Rıfkı (Springer Science and Business Media LLC, 2020-01-01)
In this study, the structure of the purified extracellular eumelanin pigment isolated from Streptomyces spp. was elucidated by detailed analysis via two different spectroscopic techniques (FT-IR and NMR). In vitro antiprol...
Synthesis of triazene-substituted homoconjugated push-pull chromophores by formal [2 + 2] cycloadditions
Erden, Kübra; Savaş, İpek; Dengiz, Çağatay (Elsevier BV, 2019-07-25)
1-(4-Ethynylphenyl)-3,3-dialkyltriaz-1-enes, well-known building blocks for branched dendrimer syntheses, were utilized as a new type of electron-donor component in formal [2 + 2] cycloadditions. The click-type, atom-econo...
Synthesis and Optoelectronic Properties of Iptycene-Naphthazarin Dyes
Dengiz, Çağatay; WU, You-Chi Mason; SWAGER, Timothy M. (2019-01-01)
We report the synthesis and characterization of iptycene-naphthazarin dyes by using a sequential Diels-Alder approach. The tautomerization of naphthazarin was used as the key step in the synthesis, with structures confirme...
The Power of Light in Hexadehydro-Diels–Alder Chemistry
Swager, Tımothy M.; Dengiz, Çağatay (2017-08-01)
A Pyrene-Capped N-Heteroacene
Swager, Tımothy M.; Dengiz, Çağatay (2017-08-01)
Naphthazarin-Polycyclic Conjugated Hydrocarbons and Iptycenes
Dengiz, Çağatay; LUPPINO, Sarah P.; GUTIERREZ, Gregory D.; SWAGER, Timothy M. (American Chemical Society (ACS), 2017-07-21)
The synthesis of a set of naphthazarin-containing polycyclic conjugated hydrocarbons is described herein. Sequential Diels-Alder reactions on a tautomerized naphthazarin core were employed to access the final conjugated sy...
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