Çağatay Dengiz

E-mail

dengizc@metu.edu.tr

Department

Department of Chemistry

ORCID

0000-0002-8238-6941

Scopus Author ID

35784358600

Web of Science Researcher ID

H-5654-2011

Synthesis, molecular modeling, DFT studies, and enantioseparation of tetrahydro-4H-chromene derivatives with calcium channel blocking activity KOÇAK ASLAN, EBRU; Karagüzel, Ayşe; Lam, Kevin; Dengiz, Çağatay; Huang, Sun; Burk, Ryan Jacob; Salehi, Reza; Sajeevan J, Siddharth Jaya; Zamponi, Gerald W.; Wolber, Gerhard; Armstrong, Daniel W.; Gündüz, Miyase Gözde (2025-05-15) Calcium channel blockers are considered effective therapeutics in cardiovascular and neurological disorders. Herein, we replaced the nitrogen atom of 1,4-dihydropyridines (DHPs), the most popular group of calcium channel b...
Design and synthesis of heterocycle-based push-pull NLOphores: A comprehensive study of their linear and non-linear optical properties Karagöllü, Başak; Şengöz, Tolga Orçun; Kayaş, Hazal; Erden, Kübra; ŞAHİN, Ertan; Esentürk, Okan; Dengiz, Çağatay (2025-01-01) Push-pull chromophores, with strong intramolecular charge transfer (ICT), exhibit high ground-state polarization, driving strong NLO responses. The donor and acceptor abilities of the groups in the investigated compounds i...
Carbamate-Functionalized NLOphores via a Formal [2+2] Cycloaddition-Retroelectrocyclization Strategy Savaş, İpek; Çelik, Mehmet Efe; Barsella, Alberto; Dengiz, Çağatay (2025-01-01) This study introduces a new donor group capable of activating click-type [2+2] cycloaddition-retroelectrocyclizations, generally known for their limited scope. Target chromophores were synthesized using isocyanate-free ure...
Synthesis and Optical Characterization of Hydrazone-Substituted Push-Pull-Type NLOphores Erden, Kübra; Soyler, Dilek; Barsella, Alberto; Sahin, Onur; Soylemez, Saniye; Dengiz, Çağatay (2024-09-10) Two distinct families of NLOphores featuring hydrazone donors were synthesized using click-type [2 + 2] cycloaddition retroelectrocyclizations (CA-RE). Despite the limitations in the substrate scope, it was shown for the f...
Synthesis, molecular modeling, DFT studies, and EPR analysis of 1,4-dihydropyridines as potential calcium channel blockers KOÇAK ASLAN, EBRU; Lam, Kevin; Dengiz, Çağatay; Denzinger, Katrin; Dicle Erdamar, Isık Yesim; Huang, Sun; Zamponi, Gerald W.; Wolber, Gerhard; GÜNDÜZ, MİYASE GÖZDE (2024-07-05) 1,4-Dihydropyridines (DHPs) are widely recognized as a highly effective class of L-type calcium channel blockers that offer significant therapeutic potential in managing cardiovascular conditions. Furthermore, their abilit...
1,3‐Diynes as Precursors for the Synthesis of Triazene‐ and Diethylaniline‐Bearing Push‐Pull NLOphores Inyurt, Fevzi Can; Dengiz, Çağatay (2024-02-01) Withinthe scopeof this study,a total of eight new NLOphoresof the D-π-A-π-Dtype have been synthesized.This was achievedby applyingclick-type[2+2] cycloaddition-retroelectrocycliza-tion reactionsof unsymmetrical1,3-diyneswi...
Click-Type Synthesis of Homoconjugated Push-Pull Chromophores: Computational Investigation of Optical and Nonlinear Optical (NLO) Properties Inyurt, Fevzi Can; Mammadova, Flora; Dengiz, Çağatay (2023-1-01) Homoconjugated push-pull chromophores were obtained by an efficient, click-type formal [2+2] cycloaddition. With these short synthetic transformations, complex chromophore structures were achieved in a single step without ...
Cyano-rich donor-acceptor-donor-type NLOphores containing dialkylated triazene and aniline groups* Mammadova, Flora; Inyurt, Fevzi Can; Barsella, Alberto; Dengiz, Çağatay (2023-01-01) Continuous progress on the synthesis of push-pull chromophores is related to their outstanding optoelectronic properties. Expanding scope is a challenge due to the instability of targets and long synthetic strategies. Here...
Evaluation of the effect of graphene oxide-based nanocomposites on smear layer by a scanning electron microscope: Laboratory investigation Sehitoglu, Gulbin; Cakici, Fatih; Soylemez, Saniye; Dengiz, Çağatay (2023-01-01) This study is to examine the effect of graphene oxide (GO) and GO-based nanocomposites (GO_EDTA, GO_CHIT) on the smear layer by scanning electron microscopy (SEM). Sixty human single-rooted anterior teeth were used. Sample...
Biphenylene-containing polycyclic conjugated compounds Dengiz, Çağatay (2023-01-01) There has been a growing emphasis on the synthesis of polycyclic conjugated compounds, driven by their distinct structural characteristics that make them valuable candidates for use in cutting-edge technologies. In particu...

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