Modification of Acrylic Bone Cements with Oxygen Plasma and Additives

Acrylic bone cements which are commonly used for the fixation of orthopedic prostheses, were prepared at different formulations, by using either ground poly(methyl methacrylate) (PMMA) particles or homogeneously synthesized PMMA microspheres with application of plasma and addition of various ingredients in order to improve mechanical and thermal properties. PMMA powders having three different particle size (ground and sieved particles with 0-50 mu m (BC1 group, average particle size: 21 mu m) and 50-150 mu m (BC2 group, average particle size: 77 mu m) and microspheres with 1 mu m (BC3 group) size) with addition of methyl methacrylate (MMA) monomer, radiopaque agent of barium sulphate (BaSO4), hydroxyapatite (HAp) and an initiator as well as other additives such as 1-dodecyl mercaptan (DDM), ammonium nitrate (AN) or zeolite particles. Among three bone cement groups, compositions prepared with PMMA particles having 50-150 mu m particle size had better handling properties and lower maximum curing temperatures. Oxygen plasma application and zeolite addition caused an increase in tensile and compressive strength and also curing temperature in all groups, while DDM and AN reduced maximum curing temperature.


Preparation, modification, and characterization of acrylic cements
Basgorenay, B; Ulubayram, K; Serbetci, K; Onurhan, E; Hasırcı, Nesrin (2006-03-15)
Acrylic cements with different compositions were prepared by mixing the solid part (composed of poly(methyl methacrylate), PMMA, and benzoyl peroxide, BPO) and the liquid part (composed of methyl methacrylate, MMA, and N,N-dimethyl-p-toluidine, DMPT), modified by addition of hydroxyapatite (HA) and ammonium nitrate (AN) and characterized by measuring thermal and mechanical properties. Three sets of samples were prepared. For B-group, the total amount of solid including HA was constant but the PMMA to HA rat...
Preparation of porous Ca-10(PO4)(6)(OH)(2) and beta-Ca-3(PO4)(2) bioceramics
Engin, NO; Tas, AC (2000-07-01)
Submicrometer-sized, pure calcium hydroxyapatite (HA, (Ca-10(PO4)(6)(OH)(2))) and eta-tricalcium phosphate (beta-TCP, Ca-3(PO4)(2)) bioceramic powders, that have been synthesized via chemical precipitation techniques, were used in the preparation of aqueous slurries that contained methyl cellulose to manufacture porous (70%-95% porosity) HA or beta-TCP ceramics. The pore sizes in HA bioceramics of this study were 200-400 mu m, whereas those of beta-TCP bioceramics were 100-300 mu m. The pore morphology and ...
Effects of Ingredients on Thermal and Mechanical Properties of Acrylic Bone Cements
Endoğan Tanır, Tuğba; Hasırcı, Nesrin (2009-09-15)
There is a very delicate relation between the amounts of all the ingredients present in the cement composition and the properties of the product. In this study, homogeneous poly(methyl methacrylate) (PMMA) microspheres were prepared by suspension polymerization technique, and used in cement formulations. Various acrylic cements with different compositions were prepared by using PMMA microspheres, methyl methacrylate (MMA) monomer, radiopaque agent of barium sulfate (BaSO4), inorganic particles of hydroxyapa...
Preparation and characterization of poly(epsilon-caprolactone) scaffolds modified with cell-loaded fibrin gel
Malikmammadov, Elbay; Endoğan Tanır, Tuğba; Kızıltay, Aysel; Hasırcı, Nesrin (2019-03-15)
Poly(epsilon-caprolactone) (PCL) is one of the most commonly used polymers in the production of tissue engineered scaffolds for hard tissue treatments. Incorporation of cells into these scaffolds significantly enhances the healing rate of the tissue. In this study, PCL scaffolds were prepared by wet spinning technique and modified by addition of fibrinogen in order to form a fibrin network between the PCL fibers. By this way, scaffolds would have micro and nanofibers in their structures. Drying of the wet s...
Modification of Poly(methyl methacrylate) Surfaces with Oxygen, Nitrogen and Argon Plasma
Ozgen, Ozge; Hasırcı, Nesrin (2014-06-01)
Poly(methyl methacrylate) (PMMA) is a strong and lightweight material used in wide range of areas changing from lenses to medical and dental devices. In this study, PMMA samples were modified by oxygen, nitrogen and argon plasma with application of 100 watts 13.56 MHz radio frequency (RF) discharge for different periods (5 min, 15 min and 30 min) and the effects of plasma parameters on surface chemistry, hydrophilicity, surface free energy and topography were examined. XPS analysis showed formation of free ...
Citation Formats
T. Endoğan Tanır, A. Kızıltay, V. N. Hasırcı, and N. Hasırcı, “Modification of Acrylic Bone Cements with Oxygen Plasma and Additives,” JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING, pp. 236–243, 2012, Accessed: 00, 2020. [Online]. Available: