Variables related to posttraumatic growth in Turkish rheumatoid arthritis patients

Dirik, Gulay
Karancı, Ayşe Nuray
Rheumatoid arthritis (RA) is a chronic, deteriorative disease, which can cause great psychological distress. Although RA has negative psychological consequences, it may also lead to positive changes, which has been given relatively little attention in the research literature. The Posttraumatic Growth Inventory (PTGI) has been used to evaluate growth in survivor's thinking, feeling and/or behavior following the experiencing of traumatic or severely adverse life events. The purpose of the current study was to examine the domains of the PTGI and to identify variables related to Posttraumatic Growth (PTG) in 117 RA patients from Turkey, a secular, Islamic, non-western developing country. Results showed that the PTGI has three domains: relationship with others; philosophy of life; and self-perception. Regression analyses showed that problem-focused coping had significant contributions to the total PTG levels and PTGI domains of relationship with others and self-perception. Perceived social support appeared as a significant associate for the total PTG levels and for all three domains. In addition, age and perceived disease severity were found to be significantly related to some domains of PTG. Clinicians, aiming to increase positive experience of RA patients, may need to focus on and facilitate perceived social support and problem-focused coping to facilitate growth experiences.


Psychological distress in rheumatoid arthritis patients: An evaluation within the conservation of resources theory
Dirik, Gulay; Karancı, Ayşe Nuray (2010-01-01)
Rheumatoid arthritis (RA) is a chronic disease, which can lead to considerable psychological distress. The present study evaluated anxiety and depression symptoms for this chronic and painful illness within the framework of the conservation of resources (COR) theory. Coping strategies, coping self-efficacy, religiousness and social support are very important personal resources, which have been found to protect individuals from psychological distress. The aim of the present study was to examine the predictiv...
Posttraumatic growth and psychological distress among rheumatoid arthritis patients : an evaluation within the conservation of resources theory
Dirik, Gülay; Karancı, Ayşe Nuray; Department of Psychology (2006)
Rheumatoid arthritis (RA) is a chronic, deteriorative disease, which leads to psychological distress. ‘Conservation of Resources theory (COR)’ is a relatively recent stress model, developed by Hobfoll (1988, 1989). This resource-oriented theory is based on the assumption that psychological stress is a reaction to a threat of loss of resources, loss of resources and/or lack of resource gain after investment in resources. Religiousness, coping abilities, coping self-efficacy and social support are very import...
Development of novel controlled release formulations of anti-tnf for rheumatoid arthritis and modeling of release behaviors
Erdemli, Özge; Tezcaner, Ayşen; Keskin, Dilek; Department of Engineering Sciences (2013)
Anti-TNFα drugs are widely used in treatment of rheumatoid arthritis. However, long term use of these drugs involves systemic effects. New era in medication involves controlled delivery systems that will provide local sustained release of drug. This study aims to develop a novel intra-articularly injectable etanercept (ETN) loaded poly(ε-caprolactone) (PCL) or methoxypoly(ethyleneglycol)-poly(ε-caprolactone)-methoxypoly(ethyleneglycol) (MPEG-PCL-MPEG) microspheres (patent pending) for the treatment of chron...
A direct relationship between oscillatory subthalamic nucleus-cortex coupling and rest tremor in Parkinson's disease
Hirschmann, Jan; Hartmann, Christian J.; Butz, Markus; Hoogenboom, Nienke; Özkurt, Tolga Esat; Elben, Saskia; Vesper, Jan; Wojtecki, Lars; Schnitzler, Alfons (2013-12-01)
Electrophysiological studies suggest that rest tremor in Parkinson's disease is associated with an alteration of oscillatory activity. Although it is well known that tremor depends on cortico-muscular coupling, it is unclear whether synchronization within and between brain areas is specifically related to the presence and severity of tremor. To tackle this longstanding issue, we took advantage of naturally occurring spontaneous tremor fluctuations and investigated cerebral synchronization in the presence an...
In vitro evaluation of effects of sustained anti-TNF release from MPEG-PCL-MPEG and PCL microspheres on human rheumatoid arthritis synoviocytes
Erdemli, Ozge; Özen, Seza; Keskin, Dilek; Usanmaz, Ali; Batu, Ezgi Deniz; Atilla, Bülent; Tezcaner, Ayşen (2014-10-01)
Anti-tumor necrosis factor (TNF) drugs such as etanercept (ETN) have been mostly used in systemic treatment of rheumatoid arthritis. To eliminate the side effects in long-term treatments and to achieve a local sustained anti-inflammatory effect, a controlled drug delivery system is needed for anti-TNF drugs. This study aims to develop novel injectable microcarriers of ETN that can provide long-term controlled release of this protein drug upon intra-articular application. In this study, poly(epsilon-caprolac...
Citation Formats
G. Dirik and A. N. Karancı, “Variables related to posttraumatic growth in Turkish rheumatoid arthritis patients,” JOURNAL OF CLINICAL PSYCHOLOGY IN MEDICAL SETTINGS, pp. 193–203, 2008, Accessed: 00, 2020. [Online]. Available: