Development of CpG ODN Based Vaccine Adjuvant Formulations.



Development of cast and heat treated 7075 alloy rifle receiver
Güngör, Ahmet Umur; Kalkanlı, Ali; Department of Metallurgical and Materials Engineering (2015)
Developing technology in the world makes products lighter and have higher strength values. That’s why, aluminum and titanium alloys start to be used instead of steel. It can be seen that 7075 aluminum alloy is one of the highest strength amongst the aluminum alloys. This alloy has a close tensile strength value to some steels, with help of the heat treatment applications and developing production technologies. Generally, industrial usage of 7075 alloy is machining of 7075 alloy extrusion slab into desired s...
Development of automobile chassis parts via aluminium extrusion and sand casting technology
Demirel, Onur; Kalkanlı, Ali; Department of Metallurgical and Materials Engineering (2012)
Due to the environmental issues related with fuel consumption and additionally passenger safety, aluminum space frame chassis is promising a big opportunity to design a lightweight structure with a high stiffness. Despite the lower stiffness and strength of aluminum in comparison to the conventional steel chassis, it can be compensated with changing thickness and design of structure by space frame geometry In this study, instead of using steel for automobile chassis, main goal is producing a space frame str...
Development of functionally graded aluminum matrix composite materials for defense industry applications
Yılmaz, Taha; Kalkanlı, Ali; Department of Metallurgical and Materials Engineering (2019)
Functionally graded materials (FGMs) are advanced class of composite materials that have a gradual change in composition and structure over the entire material and many different properties can be obtained by altering the structure. Therefore, they have many different application areas. This study aims to develop functionally graded aluminum matrix composite materials for defense applications. Firstly, porous ceramic pellets and preforms, made of alumina (Al2O3) and olivine ((Mg,Fe)SiO4), were produced with...
Development of 3-d printed exohand for mirror therapy
Yılmaz, Tunahan; Turgut, Ali Emre; Arıkan, Kutluk Bilge; Department of Mechanical Engineering (2022-11)
This thesis presents the modelling and design of a family of exoskeleton mechanisms to be used in post-stroke rehabilitation therapy. The mechanism in question is an exoskeleton worn on the index finger, and it aims to support the fingers of patients who have lost their mobility after paralysis, like a physiotherapist, and to improve motor learning in the patient in this process. Based on motor learning principles, an underactuated mechanism design has been created for this purpose, allowing the patient to ...
Development of recombinant vaccines composed of PlpE and OmpH from pasteurella multocida A:3
Okay, Sezer; Özcengiz, Gülay; Department of Biology (2011)
Pasteurella multocida serotype A:3 is a gram-negative bacterial pathogen which is one of the causative agents of shipping fever in cattle. In this study, ompH and two fragments of plpE gene (plpEN and plpEC) were cloned from the genomic DNA of P. multocida P-1062 (ATCC 15743, serotype A:3) and plpEN-ompH and plpEC-ompH fusions were constructed. In vitro expression of the genes was shown in HEK-293 cells. Later, full-length plpE gene was cloned and the recombinant proteins were expressed in E. coli and purif...
Citation Formats
M. Gürsel, “Development of CpG ODN Based Vaccine Adjuvant Formulations.,” Methods in molecular biology (Clifton, N.J.), pp. 289–98, 2016, Accessed: 00, 2020. [Online]. Available: