Pre-linguistic autism diagnostic observation schedule adapted for older individuals with severe to profound mental retardation: A pilot study

Kazak Berument, Sibel
Pickles, A
Tomlins, M
Papanikolauou, K
Lord, C
Rutter, M
The Autism Diagnostic Observational Schedule (ADOS) is a semi-structured observational scale developed to assess social interaction, communication and play in individuals who are suspected to have autism. Since the ADOS is not suitable to be used with severely or profoundly mentally retarded adolescents and adults with very limited language skills, materials and some of the tasks of the PL-ADOS and the original ADOS (the former versions of the current ADOS) were adapted. Results indicated that almost all of the overall ratings showed good reliability and discriminative diagnostic validity. Furthermore, the combination of codings into an overall algorithm score on social/communicative behavior resulted in a sensitivity of .82 and a specificity of .85 when using a cut-off score of 15.


Brief report: Autism in individuals with Down syndrome
Starr, EM; Kazak Berument, Sibel; Tomlins, M; Papanikolaou, K; Rutter, M (Springer Science and Business Media LLC, 2005-10-01)
As an off-shoot of a study examining the reliability and validity of an adapted version of the Pre-Linguistic Autism Diagnostic Observation Schedule (A-PL-ADOS), 13 individuals with Down syndrome with IQs ranging between 24 and 48 were administered the Autism Diagnostic Interview-Revised (ADI-R) and the A-PL-ADOS, which are well-validated interview and observational diagnostic measures. Three out of 13 met lifetime criteria on the ADI-R, but none of these three showed behavior that met the criterion for aut...
Documentation panels: supporting young children’s self-regulatory and metacognitive abilities
Aras, Selda; Erden, Feyza (Informa UK Limited, 2020-01-01)
It is thought that our behavioural, social and intellectual development is fostered in early childhood alongside the acquisition of metacognitive and self-regulatory abilities. This qualitative investigation reports on how 11 children applied these skills via pedagogical documentation. Participant observation and interviews were used to gather data through documentation panel activities over a period of seven weeks. Data were coded and analysed with reference to the Cambridge Independent Learning (C.Ind.Le)...
Synaptic vesicle dynamic changes in a model of fragile X
Broek, Jantine A. C.; Lin, Zhanmin; de Gruiter, H. Martijn; van 't Spijker, Heleen; Haasdijk, Elize D.; Cox, David; Özcan Kabasakal, Süreyya; van Cappellen, Gert W. A.; Houtsmuller, Adriaan B.; Willemsen, Rob; de Zeeuw, Chris I.; Bahn, Sabine (Springer Science and Business Media LLC, 2016-03-01)
Background: Fragile X syndrome (FXS) is a single-gene disorder that is the most common heritable cause of intellectual disability and the most frequent monogenic cause of autism spectrum disorders (ASD). FXS is caused by an expansion of trinucleotide repeats in the promoter region of the fragile X mental retardation gene (Fmr1). This leads to a lack of fragile X mental retardation protein (FMRP), which regulates translation of a wide range of messenger RNAs (mRNAs). The extent of expression level alteration...
Preschool Movement Education in Turkey: Perceptions of Preschool Administrators and Parents
Sevimli Çelik, Serap; Kirazcı, Sadettin; İnce, Mustafa Levent (Springer Science and Business Media LLC, 2011-12-01)
The purpose of this study was to examine the perceptions of preschool administrators and parents about preschool movement education and movement practices in preschools. Participants were 8 preschool administrators and 21 parents from 8 randomly selected private preschools in one of the municipalities in Ankara, Turkey. Semi-structured interviews, field visits, and observations were conducted, and written documents were collected. The findings indicate that preschool administrators and parents have limited ...
Evaluation of a tangible mobile application for students with specific learning disabilities
Polat, Elif; Çağıltay, Kürşat; AYKUT, ÇIĞIL; KARASU, NECDET (Informa UK Limited, 2019-01-02)
Students with specific learning disabilities (SLD) typically do not perform at the expected levels of academic achievement. Tangible mobile applications are learning devices that allow for physical engagement and multisensory interaction. They present as promising tools to facilitate learning for students with SLD. This study explored the use of a tangible mobile application for assisting three seventh-grade Turkish students with SLD to learn scientific principles regarding cell concepts. A multiple-probede...
Citation Formats
S. Kazak Berument, A. Pickles, M. Tomlins, K. Papanikolauou, C. Lord, and M. Rutter, “Pre-linguistic autism diagnostic observation schedule adapted for older individuals with severe to profound mental retardation: A pilot study,” JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, pp. 821–829, 2005, Accessed: 00, 2020. [Online]. Available: