Robust background normalization method for one-channel microarrays

Date

2017-04-01

Author

AKAL, TÜLAY
Purutçuoğlu Gazi, Vilda
Weber, Gerhard-Wilhelm

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Background: Microarray technology, aims to measure the amount of changes in transcripted messages for each gene by RNA via quantifying the colour intensity on the arrays. But due to the different experimental conditions, these measurements can include both systematic and random erroneous signals. For this reason, we present a novel gene expression index, called multi-RGX (Multiple-probe Robust Gene Expression Index) for one-channel microarrays.

Subject Keywords

Clinical Biochemistry, Biochemistry, Molecular Biology, Biochemistry, medical

URI

https://hdl.handle.net/11511/41767

Collections

Department of Statistics, Article