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Robust background normalization method for one-channel microarrays
Date
2017-04-01
Author
AKAL, TÜLAY
Purutçuoğlu Gazi, Vilda
Weber, Gerhard-Wilhelm
Metadata
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This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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Background: Microarray technology, aims to measure the amount of changes in transcripted messages for each gene by RNA via quantifying the colour intensity on the arrays. But due to the different experimental conditions, these measurements can include both systematic and random erroneous signals. For this reason, we present a novel gene expression index, called multi-RGX (Multiple-probe Robust Gene Expression Index) for one-channel microarrays.
Subject Keywords
Clinical Biochemistry
,
Biochemistry
,
Molecular Biology
,
Biochemistry, medical
URI
https://hdl.handle.net/11511/41767
Journal
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
DOI
https://doi.org/10.1515/tjb-2016-0231
Collections
Department of Statistics, Article